Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C24H29N5O2 |
| Molecular Weight | 419.5194 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]12C=C[C@]1([H])[C@@H]3C=C[C@H]2[C@@]4([H])C(=O)N(CCCCN5CCN(CC5)C6=NC=CC=N6)C(=O)[C@@]34[H]
InChI
InChIKey=AERLHOTUXIJQFV-RCPZPFRWSA-N
InChI=1S/C24H29N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3-9,16-21H,1-2,10-15H2/t16-,17+,18-,19+,20-,21+
| Molecular Formula | C24H29N5O2 |
| Molecular Weight | 419.5194 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Zalospirone is a selective partial agonist of 5HT1A receptor developed by Wyeth. It was investigated in clinical trials in major depression. Although the highest dose of the drug seemed to have significant antidepressant efficacy, it was not well tolerated and by the 6th week more than half of patients in the high-dose group has dropped out.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 17:03:33 GMT 2023
by
admin
on
Sat Dec 16 17:03:33 GMT 2023
|
| Record UNII |
0449O95Z1J
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Official Name | English | ||
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Code | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C265
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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NCI_THESAURUS |
C28197
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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100000079387
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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ZALOSPIRONE
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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DTXSID501028422
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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C152944
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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CHEMBL2110887
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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114298-18-9
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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163925
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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6754
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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SUB00133MIG
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
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PRIMARY | |||
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0449O95Z1J
Created by
admin on Sat Dec 16 17:03:33 GMT 2023 , Edited by admin on Sat Dec 16 17:03:33 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
