Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C24H29N5O2 |
| Molecular Weight | 419.5194 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1[C@H]2[C@H]([C@H]3C=C[C@@H]2[C@@H]4C=C[C@H]34)C(=O)N1CCCCN5CCN(CC5)C6=NC=CC=N6
InChI
InChIKey=AERLHOTUXIJQFV-RCPZPFRWSA-N
InChI=1S/C24H29N5O2/c30-22-20-18-6-7-19(17-5-4-16(17)18)21(20)23(31)29(22)11-2-1-10-27-12-14-28(15-13-27)24-25-8-3-9-26-24/h3-9,16-21H,1-2,10-15H2/t16-,17+,18-,19+,20-,21+
| Molecular Formula | C24H29N5O2 |
| Molecular Weight | 419.5194 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 6 / 6 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Zalospirone is a selective partial agonist of 5HT1A receptor developed by Wyeth. It was investigated in clinical trials in major depression. Although the highest dose of the drug seemed to have significant antidepressant efficacy, it was not well tolerated and by the 6th week more than half of patients in the high-dose group has dropped out.
Originator
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 08:42:47 GMT 2025
by
admin
on
Wed Apr 02 08:42:47 GMT 2025
|
| Record UNII |
0449O95Z1J
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| Record Status |
Validated (UNII)
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| Record Version |
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-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Preferred Name | English | ||
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Official Name | English | ||
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Common Name | English | ||
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Common Name | English | ||
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Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C265
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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NCI_THESAURUS |
C28197
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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100000079387
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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ZALOSPIRONE
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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DTXSID501028422
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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C152944
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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CHEMBL2110887
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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114298-18-9
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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163925
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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6754
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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SUB00133MIG
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY | |||
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0449O95Z1J
Created by
admin on Wed Apr 02 08:42:47 GMT 2025 , Edited by admin on Wed Apr 02 08:42:47 GMT 2025
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
