TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:59:13 GMT 2025` Edited by `admin` on `Tue Apr 01 16:59:13 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	042U4WAS57
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GP80-LNGFR

Preferred Name

English

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 16

Common Name

English

CD271

Common Name

English

P75 ICD

Common Name

English

TNFRSF16

Common Name

English

LOW AFFINITY NEUROTROPHIN RECEPTOR P75NTR

Common Name

English

Code System Code Type Description

FDA UNII

042U4WAS57

Created by admin on Tue Apr 01 16:59:13 GMT 2025 , Edited by admin on Tue Apr 01 16:59:13 GMT 2025

PRIMARY

UNIPROT

P08138

Created by admin on Tue Apr 01 16:59:13 GMT 2025 , Edited by admin on Tue Apr 01 16:59:13 GMT 2025

PRIMARY

PHAROS

P08138

Created by admin on Tue Apr 01 16:59:13 GMT 2025 , Edited by admin on Tue Apr 01 16:59:13 GMT 2025

PRIMARY

From	To
1_4	1_15
1_16	1_29
1_19	1_36
1_39	1_55
1_58	1_71
1_61	1_79
1_81	1_94
1_97	1_110
1_100	1_118
1_121	1_136
1_139	1_152
1_142	1_160

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_32

Related Record Type Details


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LM-11A-31

LIGAND->TARGET

Comments:

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Amount:


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NERVE GROWTH FACTOR

AGONIST -> TARGET

Comments:

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Amount:


					4DL2E33KNV

CHF-6467

NON-INHIBITOR->OFF TARGET

Comments:

Mutation (R100E) selectively disrupts the binding of hNGF to the p75NTR receptor while maintaining the affinity for the TrkA receptor.

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_283]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL
Molecular Formula	CHEMICAL