Efranarelaxin alfa

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 09:46:23 GMT 2025` Edited by `admin` on `Wed Apr 02 09:46:23 GMT 2025`
Protein Type	FUSION PROTEINS
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	03X92LE3ZC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Efranarelaxin alfa

Official Name

English

Immunoglobulin G1 [14-phenylalanine,15-glutamic acid,111-serine,134-cysteine,146-tryptophan,de-C-terminal lysine], (human ?1-chain C-region C-terminal fragment) fusion protein with peptide linker ((GGGGS)3GGGGGS) fusion protein with relaxin H2 A-chain (h

Preferred Name

English

efranarelaxin alfa [INN]

Common Name

English

human immunoglobulin G1 (IgG1) Fc fragment (h-CH2-CH3-CHS domains) (1-226) [Homo sapiens IGHG1*03 (hinge (1-10), CH2 L14>F, L15>E, P111>S (11-120), CH3 S134>C, T146>W (121-225), CHS K227>del (226))]

Common Name

English

Code System Code Type Description

CAS

2969217-22-7

Created by admin on Wed Apr 02 09:46:23 GMT 2025 , Edited by admin on Wed Apr 02 09:46:23 GMT 2025

PRIMARY

FDA UNII

03X92LE3ZC

Created by admin on Wed Apr 02 09:46:23 GMT 2025 , Edited by admin on Wed Apr 02 09:46:23 GMT 2025

PRIMARY

INN

13420

Created by admin on Wed Apr 02 09:46:23 GMT 2025 , Edited by admin on Wed Apr 02 09:46:23 GMT 2025

PRIMARY

From	To
2_147	2_205
2_41	2_101
1_271	2_269
1_258	2_257
1_257	1_262
1_147	1_205
1_134	2_129
1_41	1_101
1_9	2_9
1_6	2_6

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_77
N	2_77

Related Record Type Details


					JCD025N53A

RELAXIN RECEPTOR 1

TARGET -> AGONIST

Interaction Type:

IN-VITRO

Amount:

Related Record Type Details


					03X92LE3ZC

Efranarelaxin alfa

ACTIVE MOIETY

Comments:

relaxin analogue

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL