Dalmitamig

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:27:32 GMT 2025` Edited by `admin` on `Wed Apr 02 07:27:32 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	02Z59O1UOM
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

REGN-7075

Preferred Name

English

Dalmitamig

Official Name

English

dalmitamig [INN]

Common Name

English

Immunoglobulin G4 [230-proline,235-proline,236-valine,237-alanine,de-238-glycine,436-arginine,437-phenylalanine,446-proline], anti-(human CD28 antigen) (human monoclonal REGN7075 ?4-chain), disulfide with human monoclonal REGN7075 ?-chain,(228?227'),(231

Common Name

English

REGN 7075 [WHO-DD]

Common Name

English

REGN7075

Code

English

DALMITAMIG [USAN]

Common Name

English

Code System Code Type Description

CAS

2765077-69-6

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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INN

13010

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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USAN

LM-18

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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SMS_ID

300000025422

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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NCI_THESAURUS

C178284

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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FDA UNII

02Z59O1UOM

Created by admin on Wed Apr 02 07:27:32 GMT 2025 , Edited by admin on Wed Apr 02 07:27:32 GMT 2025

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From	To
4_135	4_195
4_23	4_89
3_135	3_195
3_23	3_89
2_367	2_425
2_261	2_321
2_148	2_204
2_135	4_215
2_22	2_95
1_368	1_426
1_262	1_322
1_231	2_230
1_228	2_227
1_149	1_205
1_136	3_215
1_22	1_95

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_297

Related Record Type Details


					02Z59O1UOM

ACTIVE MOIETY

Comments:

Bridge EGFR positive tumor cells with CD28 positive T cells and provide amplified TCR-CD3 complex-mediated T cell activation within the tumor through the activation of CD28 signaling.

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL