U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C15H23N5O4
Molecular Weight 337.3742
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of KYOTORPHIN

SMILES

N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O

InChI

InChIKey=JXNRXNCCROJZFB-RYUDHWBXSA-N
InChI=1S/C15H23N5O4/c16-11(8-9-3-5-10(21)6-4-9)13(22)20-12(14(23)24)2-1-7-19-15(17)18/h3-6,11-12,21H,1-2,7-8,16H2,(H,20,22)(H,23,24)(H4,17,18,19)/t11-,12-/m0/s1

HIDE SMILES / InChI

Molecular Formula C15H23N5O4
Molecular Weight 337.3742
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Effect of kyotorphin on the seizure activity induced by kainic acid during picrotoxin kindling in rats].
1998 Jan-Feb
Conjugation with L-Glutamate for in vivo brain drug delivery.
2001
Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus.
2002 Apr 15
Separation and determination of l-tyrosine and its metabolites by capillary zone electrophoresis with a wall-jet amperometric detection.
2006 Dec 15
Kyotorphin suppresses proliferation and Ca2+ signaling in brown preadipocytes.
2006 Feb
Kyotorphin has a novel action on rat cardiac muscle.
2006 Jan 20
Chiral recognition of D-kyotorphin by lipidic membranes: relevance toward improved analgesic efficiency.
2006 Jul
The Analgesic Activity of Bestatin as a Potent APN Inhibitor.
2010
Moisture-induced solid state instabilities in alpha-chymotrypsin and their reduction through chemical glycosylation.
2010 Aug 9
Membrane-induced conformational changes of kyotorphin revealed by molecular dynamics simulations.
2010 Sep 9
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:05:06 GMT 2023
Edited
by admin
on Fri Dec 15 18:05:06 GMT 2023
Record UNII
02N30CW3X0
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
KYOTORPHIN
Common Name English
DIPEPTIDE-1
INCI  
INCI  
Official Name English
DIPEPTIDE-1 [INCI]
Common Name English
L-TYROSYL-L-ARGININE
Systematic Name English
TYR-ARG
Common Name English
Code System Code Type Description
CHEBI
58184
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
PUBCHEM
123804
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
CAS
70904-56-2
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
WIKIPEDIA
KYOTORPHIN
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
EPA CompTox
DTXSID40221136
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
MESH
C019448
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
FDA UNII
02N30CW3X0
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
CHEBI
17537
Created by admin on Fri Dec 15 18:05:07 GMT 2023 , Edited by admin on Fri Dec 15 18:05:07 GMT 2023
PRIMARY
Related Record Type Details
TRANSPORTER -> INHIBITOR