DescriptionCurator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401
Curator's Comment: description was created based on several sources, including
https://www.ncbi.nlm.nih.gov/books/NBK215133/ | https://www.iaea.org/OurWork/ST/NE/NEFW/Technical-Areas/RRS/documents /mo99/WORKINGMATERIALSmo99CM.pdf | https://www.ncbi.nlm.nih.gov/pubmed/27854401
Molybdenum-99 (99Mo, half-life = 66 h) is a parent radionuclide of a diagnostic nuclear isotope. It decays in technetium-99 m (half-life = 6 h), which is used in over 30 million procedures per year around the world. Between 95 and 98 percent of Mo-99 is currently being produced using highly enriched uranium (HEU) targets. Other medical isotopes such as iodine-131 (I-131) and xenon-133 (Xe-133) are by-products of the Mo-99 production process and will be sufficiently available if Mo-99 is available.
Approval Year
Conditions
| Condition | Modality | Targets | Highest Phase | Product |
|---|---|---|---|---|
| Diagnostic | OSTEOLITE Approved UseUnknown Launch Date1977 |
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| Diagnostic | DRAXIMAGE MDP-10 Approved UseMDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate) may be used as a bone imaging agent to delineate areas of altered osteogenesis. Launch Date1978 |
| Substance Class |
Protein
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| Protein Type | MONOCLONAL ANTIBODY |
| Protein Sub Type | IGG1 |
| Sequence Origin | MOUSE |
| Sequence Type | COMPLETE |
| Record UNII |
029JF1SCU8
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| Record Status |
Validated (UNII)
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| Record Version |
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| Classification Tree | Code System | Code | ||
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EMA ASSESSMENT REPORTS |
CEA-SCAN (WITHDRAWN: COLORECTAL NEOPLASMS)
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WHO-ATC |
V09IA06
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| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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Technetium (99mTc) arcitumomab
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230435
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PRIMARY | RxNorm | ||
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029JF1SCU8
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PRIMARY | |||
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m2034
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PRIMARY | Merck Index | ||
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154361-49-6
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DB00113
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CHEMBL1743090
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PRIMARY |
| Glycosylation Type | MAMMALIAN |
| Glycosylation Link Type | Site |
|---|---|
| N | 1_296 |
| N | 2_296 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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STARTING MATERIAL -> INGREDIENT | |||
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TARGET->RADIOLIGAND |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY | |||
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ACTIVE MOIETY |
| Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
|---|---|---|---|---|---|---|
| MOL_WEIGHT:NUMBER(CALCULATED) | CHEMICAL |
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| Molecular Formula | CHEMICAL |
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