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Details

Stereochemistry MIXED
Molecular Formula C14H24N4
Molecular Weight 248.3672
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of 2,2'-AZOBIS(2,4-DIMETHYLVALERONITRILE)

SMILES

CC(C)CC(C)(C#N)\N=N\C(C)(CC(C)C)C#N

InChI

InChIKey=WYGWHHGCAGTUCH-ISLYRVAYSA-N
InChI=1S/C14H24N4/c1-11(2)7-13(5,9-15)17-18-14(6,10-16)8-12(3)4/h11-12H,7-8H2,1-6H3/b18-17+

HIDE SMILES / InChI

Molecular Formula C14H24N4
Molecular Weight 248.3672
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 2
E/Z Centers 1
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Evaluation of antioxidant properties of Mallotus oppositifolium in in-vitro, in-vivo and ex-vivo model systems.
2010-12
Protection by Exogenously Added Coenzyme Q(9) against Free Radical-Induced Injuries in Human Liver Cells.
2010-05
Lipid oxidation in water-in-olive oil emulsions initiated by a lipophilic radical source.
2010-03-18
Molecular mechanism of recombinant liver fatty acid binding protein's antioxidant activity.
2009-12
Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and mRNA levels of HMG-CoA reductase and cholesterol 7alpha-hydroxylase in primary rat hepatocytes.
2008-07-09
Identification of 2,3-dimethyl-2,3-diisobutyl succinonitrile in laser printer emissions.
2008
Spin-labelled lutein as a new antioxidant in protection against lipid peroxidation.
2007-09
Nonenzymatic antioxidative and antiglycative effects of oleanolic acid and ursolic acid.
2007-08-22
Kinetics of the lipoperoxyl radical-scavenging activity of indicaxanthin in solution and unilamellar liposomes.
2007-02
Effect of various radical generators on insulin-dependent regulation of hepatic gene expression.
2007-01
Antioxidant effect of Wen-Pi-Tang and its component crude drugs on oxidative stress.
2007
Procyanidins protect Caco-2 cells from bile acid- and oxidant-induced damage.
2006-10-15
Mechanisms of cardiolipin oxidation by cytochrome c: relevance to pro- and antiapoptotic functions of etoposide.
2006-08
High-throughput quantitation of peroxyl radical scavenging capacity in bulk oils.
2006-07-26
Diiron amido-imido complex [(CpFe)2(mu2-NHPh)(mu2-NPh)]: synthesis and a net hydrogen atom abstraction reaction to form a bis(imido) complex.
2006-06-26
New method for the synthesis of N-tert-alkoxyarylaminyl radicals.
2006-06-23
Quantification of lipid alkyl radicals trapped with nitroxyl radical via HPLC with postcolumn thermal decomposition.
2005-11
Modified protein carbonyl assay detects oxidised membrane proteins: a new tool for assessing drug- and chemically-induced oxidative cell injury.
2005-09-14
Antioxidant activity of gamma-oryzanol: mechanism of action and its effect on oxidative stability of pharmaceutical oils.
2005-08-11
Synergistic effects of zeaxanthin and its binding protein in the prevention of lipid membrane oxidation.
2005-05-30
Aromatic and aliphatic mono- and bis-nitroxides: a study on their radical scavenging abilities.
2005-03
Photodecomposition of retinyl palmitate in ethanol by UVA light-formation of photodecomposition products, reactive oxygen species, and lipid peroxides.
2005-02
The interaction of flavonoids with membranes: potential determinant of flavonoid antioxidant effects.
2004-12
Differential antioxidant properties of red wine in water soluble and lipid soluble peroxyl radical generating systems.
2004-08
Inhibition by uric acid of free radicals that damage biological molecules.
2003-12
A lipophilic free radical initiator, 2,2'-azobis (2,4-dimethylvaleronitrile) (AMVN) enhances caspase-dependent apoptosis induced by hyperthermia.
2003-03-08
Site-activity relationship of nitroxide radical's antioxidative effect.
2003-01-15
Hydroxyl radical scavenging action of capsaicin.
2002
Antioxidant mechanism of carnosic acid: structural identification of two oxidation products.
2001-11
Antioxidative activity of 3,4-dihydroxyphenylacetic acid and caffeic acid in rat plasma.
2001-10
Cytotoxicity of reactive oxygen species and related agents toward undifferentiated and differentiated rat phenochromocytoma PC12 cells.
2001-05
Quantitative analysis of phospholipid peroxidation and antioxidant protection in live human epidermal keratinocytes.
2001-02
Antioxidative effect of fluvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on peroxidation of phospholipid liposomes.
2001-02
Antioxidant effect of capsaicin on lipid peroxidation in homogeneous solution, micelle dispersions and liposomal membranes.
2001
Patents
Substance Class Chemical
Created
by admin
on Wed Apr 02 10:33:04 GMT 2025
Edited
by admin
on Wed Apr 02 10:33:04 GMT 2025
Record UNII
02830LWZ4X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ADVN
Preferred Name English
2,2'-AZOBIS(2,4-DIMETHYLVALERONITRILE)
Systematic Name English
PENTANENITRILE, 2,2'-(1E)-1,2-DIAZENEDIYLBIS(2,4-DIMETHYL-
Systematic Name English
PENTANENITRILE, 2,2'-AZOBIS(2,4-DIMETHYL-
Systematic Name English
PENTANENITRILE, 2,2'-(1,2-DIAZENEDIYL)BIS(2,4-DIMETHYL-
Systematic Name English
2,2'-AZOBIS(2,4-DIMETHYLPENTANENITRILE)
Systematic Name English
VALERONITRILE, 2,2'-AZOBIS(2,4-DIMETHYL-
Systematic Name English
Code System Code Type Description
ECHA (EC/EINECS)
224-583-8
Created by admin on Wed Apr 02 10:33:04 GMT 2025 , Edited by admin on Wed Apr 02 10:33:04 GMT 2025
PRIMARY
EPA CompTox
DTXSID3044675
Created by admin on Wed Apr 02 10:33:04 GMT 2025 , Edited by admin on Wed Apr 02 10:33:04 GMT 2025
PRIMARY
FDA UNII
02830LWZ4X
Created by admin on Wed Apr 02 10:33:04 GMT 2025 , Edited by admin on Wed Apr 02 10:33:04 GMT 2025
PRIMARY
CAS
4419-11-8
Created by admin on Wed Apr 02 10:33:04 GMT 2025 , Edited by admin on Wed Apr 02 10:33:04 GMT 2025
PRIMARY
CAS
1547296-70-7
Created by admin on Wed Apr 02 10:33:04 GMT 2025 , Edited by admin on Wed Apr 02 10:33:04 GMT 2025
ALTERNATIVE