CYANOCOBALAMIN CO-57

US Previously Marketed

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C62H89N13O14P.CN.Co
Molecular Weight	1354.3762
Optical Activity	UNSPECIFIED
Defined Stereocenters	13 / 14
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[57Co+3].[C-]#N.C[C@H](CNC(=O)CC[C@]1(C)[C@@H](CC(N)=O)C2[N-]C1=C(C)C3=NC(=CC4=NC(=C(C)C5=N[C@]2(C)[C@@](C)(CC(N)=O)[C@@H]5CCC(N)=O)[C@@](C)(CC(N)=O)[C@@H]4CCC(N)=O)C(C)(C)[C@@H]3CCC(N)=O)OP([O-])(=O)O[C@@H]6[C@@H](CO)O[C@@H]([C@@H]6O)N7C=[NH]C8=CC(C)=C(C)C=C78

InChI

InChIKey=FDJOLVPMNUYSCM-LFHMENBZSA-L

InChI=1S/C62H90N13O14P.CN.Co/c1-29-20-39-40(21-30(29)2)75(28-70-39)57-52(84)53(41(27-76)87-57)89-90(85,86)88-31(3)26-69-49(83)18-19-59(8)37(22-46(66)80)56-62(11)61(10,25-48(68)82)36(14-17-45(65)79)51(74-62)33(5)55-60(9,24-47(67)81)34(12-15-43(63)77)38(71-55)23-42-58(6,7)35(13-16-44(64)78)50(72-42)32(4)54(59)73-56;1-2;/h20-21,23,28,31,34-37,41,52-53,56-57,76,84H,12-19,22,24-27H2,1-11H3,(H15,63,64,65,66,67,68,69,71,72,73,74,77,78,79,80,81,82,83,85,86);;/q;-1;+3/p-2/t31-,34-,35-,36-,37+,41-,52-,53-,56?,57+,59-,60+,61+,62+;;/m1../s1/i;;1-2

HIDE SMILES / InChI

Molecular Formula	Co
Molecular Weight	56.936296235
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C62H87N13O14P
Molecular Weight	1269.4066
Charge	-3
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	13 / 14
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	CHN
Molecular Weight	27.0253
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4473962 | https://www.ncbi.nlm.nih.gov/pubmed/5388267 | https://www.ncbi.nlm.nih.gov/pubmed/14226585

Cyanocobalamin Co 57 is a manufactured form of radiolabeled vitamin B indicated as an adjunct in diagnosing intestinal cyanocobalamin malabsorption syndromes due to lack of intrinsic factor (IF) or other defects in intestinal absorption (e.g., blind loop syndrome and diverticulitis, celiac disease, Crohn's disease, lesions in the small intestine, severe pancreatitis, tropical sprue).

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Pernicious Anemia 1 Sources: https://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/016635Orig1s000.pdf	Diagnostic		Approved 8583	CYANOCOBALAMIN CO 57 SCHILLING TEST KIT Approved Use Unknown Launch Date 1968

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:55:51 GMT 2025` Edited by `admin` on `Mon Mar 31 17:55:51 GMT 2025`
Record UNII	025P9I542Y
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CYANOCOBALAMIN CO 57

Preferred Name

English

CYANOCOBALAMIN CO-57

Common Name

English

CYANOCOBALAMIN (57CO)

Official Name

English

(57CO)VITAMIN B12

Common Name

English

CYANOCOBALAMIN CO-57 [ORANGE BOOK]

Common Name

English

CYANOCOBALAMIN CO 57 [USP IMPURITY]

Common Name

English

CYANOCOBALAMIN, CO-57

Common Name

English

CYANOCOBALAMIN,CO-57 [VANDF]

Common Name

English

CYANOCOBALAMIN (57 CO)

Common Name

English

RUBRATOPE-57 KIT COMPONENT CYANOCOBALAMIN CO-57

Common Name

English

Cyanocobalamin (57 co) [WHO-DD]

Common Name

English

COBALT (57CO) CYANOCOBALAMIN

Common Name

English

CYANOCOBALAMIN CO 57 SCHILLING TEST KIT COMPONENT CYANOCOBALAMIN CO-57

Common Name

English

CYANOCOBALAMIN CO57

Common Name

English

VITAMIN B12, CO-57

Common Name

English

CYANOCOBALAMIN,CO-57

Common Name

English

CYANOCOBALAMIN CO 57 [USAN]

Common Name

English

DICOPAC KIT COMPONENT CYANOCOBALAMIN CO-57

Common Name

English

RADIOACTIVE 57CO VITAMIN B12 [MI]

Common Name

English

cyanocobalamin (??Co) [INN]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000177914