TETRAMETHYLTHIURAM MONOSULFIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

US Approved Allergenic Extract (1994)

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H12N2S3
Molecular Weight	208.368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TETRAMETHYLTHIURAM MONOSULFIDE

Structure Search

SMILES

CN(C)C(=S)SC(=S)N(C)C

InChI

InChIKey=REQPQFUJGGOFQL-UHFFFAOYSA-N

InChI=1S/C6H12N2S3/c1-7(2)5(9)11-6(10)8(3)4/h1-4H3

HIDE SMILES / InChI

Molecular Formula	C6H12N2S3
Molecular Weight	208.368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: http://www.chemotechnique.se/get_pdf.php?l=en&p=263

Tetramethylthiuram monosulfide (TMTM) is used as a secondary accelerator and activator in the processing of natural and butyl rubbers. It is used as a fungicide, and insecticide.

Approval Year

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

PubMed

Title	Date	PubMed
Allergic contact dermatitis from natural latex.	2001 Sep	11526517
Contact allergy to thiurams: multifactorial analysis of clinical surveillance data collected by the IVDK network.	2010 Aug	20041260
Dithiocarbamates induce craniofacial abnormalities and downregulate sox9a during zebrafish development.	2010 Sep	20530235

Patents

Patents

Sample Use Guides

In Vivo Use Guide

adult female Wistar rats were administrated by gavage of tetramethyl thiurammonosulfide (TMTM, 2 mmol/kg)

Route of Administration: Intragastric

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:31:26 GMT 2023` Edited by `admin` on `Fri Dec 15 15:31:26 GMT 2023`
Record UNII	01W430XXSQ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TETRAMETHYLTHIURAM MONOSULFIDE

Systematic Name

English

BISDIMETHYLTHIOCARBAMYL SULFIDE

Common Name

English

NSC-4767

Code

English

N,N,N',N'-TETRAMETHYLTHIURAM MONOSULFIDE

Systematic Name

English

BISDIMETHYLTHIOCARBAMYL SULPHIDE

Common Name

English

BIS(DIMETHYLTHIOCARBAMOYL) SULFIDE [HSDB]

Common Name

English

NSC-3400

Code

English

TETRAMETHYLTHIURAM MONOSULPHIDE

Systematic Name

English

Classification Tree Code System Code

NDF-RT

N0000185508

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

Code System Code Type Description

NDF-RT

N0000171131

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

Allergens [Chemical/Ingredient]

DAILYMED

01W430XXSQ

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

NDF-RT

N0000184306

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

Cell-mediated Immunity [PE]

NSC

4767

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

HSDB

2902

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

CAS

97-74-5

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

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NSC

3400

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

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FDA UNII

01W430XXSQ

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

EVMPD

SUB61038

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

MESH

C034033

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

NDF-RT

N0000175629

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

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Increased Histamine Release [PE]

RXCUI

1363713

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

RxNorm

SMS_ID

100000134279

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

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DRUG BANK

DB14178

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

ECHA (EC/EINECS)

202-605-7

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

EPA CompTox

DTXSID0021333

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

PUBCHEM

7347

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

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WIKIPEDIA

Tetramethylthiuram sulfide

Created by admin on Fri Dec 15 15:31:26 GMT 2023 , Edited by admin on Fri Dec 15 15:31:26 GMT 2023

PRIMARY

Related Record Type Details


					01W430XXSQ

TETRAMETHYLTHIURAM MONOSULFIDE

ACTIVE MOIETY

Amount: