U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Thu Jul 06 19:33:04 UTC 2023
Edited
by admin
on Thu Jul 06 19:33:04 UTC 2023
Protein Type TRANSPORTER
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
0189J4XE1H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR F508 DELETED
Common Name English
CFTR F508DEL
Common Name English
CFTR.DELTA.F508
Common Name English
Code System Code Type Description
UNIPROT
P13569
Created by admin on Thu Jul 06 19:33:05 UTC 2023 , Edited by admin on Thu Jul 06 19:33:05 UTC 2023
PRIMARY
FDA UNII
0189J4XE1H
Created by admin on Thu Jul 06 19:33:05 UTC 2023 , Edited by admin on Thu Jul 06 19:33:05 UTC 2023
PRIMARY
Glycosylation Link Type Site
N 1_893
N 1_899
Related Record Type Details
CORRECTOR->TARGET
Rescues CFTR folding and trafficking to the plasma membrane.
CORRECTOR->TARGET
Improve the processing of CFTR
improve the processing and trafficking of CFTR protein to the cell surface
EC50
CORRECTOR->TARGET
CORRECTOR->TARGET
Improve the processing of CFTR
improve the processing and trafficking of CFTR protein to the cell surface
EC50
COMPLEMENTARY RNA TO REPAIR TARGET MRNA->TARGET
ACTIVATOR -> TARGET
Potentiator
ACTIVATOR -> TARGET
CORRECTOR->TARGET
ACTIVATOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL