Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H22N2O2 |
| Molecular Weight | 262.3474 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)NCC(O)COC1=CC=CC2=C1C=C(C)N2
InChI
InChIKey=NXWGWUVGUSFQJC-UHFFFAOYSA-N
InChI=1S/C15H22N2O2/c1-10(2)16-8-12(18)9-19-15-6-4-5-14-13(15)7-11(3)17-14/h4-7,10,12,16-18H,8-9H2,1-3H3
| Molecular Formula | C15H22N2O2 |
| Molecular Weight | 262.3474 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Mepindolol is a selective beta1-adrenoreceptor blocker with intrinsic sympathetic activity. Treatment with mepindolol dose not significantly affect the lipid levels - the total cholesterol in plasma was decreased by mepindolol but HDL-cholesterol increased. During beta-receptor blockade with mepindolol-sulfate angina was compensated, the unfavourable hemodynamic effects seen during placebo did not occur. No signs of congestive heart failure were found during mepindolol-sulfate-therapy. Mepindolol-sulfate showed a pronounced blood-pressure lowering effect.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of chemical structure in stereoselective recognition of beta-blockers by cyclodextrins in capillary zone electrophoresis. | 2008-04-24 |
|
| Transdermal delivery of beta-blockers. | 2006-05 |
|
| Role of chemical structure in stereoselective recognition of beta-blockers and H1-antihistamines by human serum transferrin in capillary zone electrophoresis. | 2006-04 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 09:46:38 GMT 2025
by
admin
on
Wed Apr 02 09:46:38 GMT 2025
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| Record UNII |
00Q31ER368
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| Record Status |
Validated (UNII)
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| Record Version |
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Preferred Name | English | ||
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Official Name | English | ||
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C29576
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WHO-ATC |
C07AA14
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WHO-VATC |
QC07AA14
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| Code System | Code | Type | Description | ||
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C84659
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DB13530
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29518
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00Q31ER368
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71698
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4001
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100000081477
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245-831-1
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C015340
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23694-81-7
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DTXSID40865110
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m7193
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1697
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MEPINDOLOL
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CHEMBL65717
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SUB08750MIG
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| Related Record | Type | Details | ||
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SALT/SOLVATE -> PARENT |
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ACTIVE MOIETY |
