BATANOPRIDE HYDROCHLORIDE

Details

Stereochemistry	RACEMIC
Molecular Formula	C17H26ClN3O3.ClH
Molecular Weight	392.321
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCN(CC)CCNC(=O)C1=C(OC(C)C(C)=O)C=C(N)C(Cl)=C1

InChI

InChIKey=CUTCEGXKJDBAFQ-UHFFFAOYSA-N

InChI=1S/C17H26ClN3O3.ClH/c1-5-21(6-2)8-7-20-17(23)13-9-14(18)15(19)10-16(13)24-12(4)11(3)22;/h9-10,12H,5-8,19H2,1-4H3,(H,20,23);1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C17H26ClN3O3
Molecular Weight	355.86
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1855280 | https://www.ncbi.nlm.nih.gov/pubmed/2978041

Batanopride, previously known as BMY-25801, a 5-hydroxytryptamine 3 receptor antagonist, was studied against emesis for cancer patients that were treated by chemotherapy procedure. Batanopride had the dose-limiting side effects including hypotension and long QT syndrome that is why any further experiments for its medical application were discontinued.

Originator

Approval Year

PubMed

Title	Date	PubMed
BMY-25801, an antiemetic agent free of D2-dopamine receptor antagonist properties.	1988 Mar	2978041
A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy.	1991 Oct	1742224

Sample Use Guides

In Vivo Use Guide

six patient groups each received a single intravenous dose of batanopride ranging from 0.2 to 6.0 mg/kg

Route of Administration: Intravenous

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:34:27 GMT 2023` Edited by `admin` on `Fri Dec 15 17:34:27 GMT 2023`
Record UNII	00L331RFEC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BATANOPRIDE HYDROCHLORIDE

Official Name

English

BMY-25801-01

Code

English

BENZAMIDE, 4-AMINO-5-CHLORO-N-(2-(DIETHYLAMINO)ETHYL)-2-(1-METHYL-2-OXOPROPOXY)-, MONOHYDROCHLORIDE

Common Name

English

Batanopride hydrochloride [WHO-DD]

Common Name

English

BATANOPRIDE HYDROCHLORIDE [USAN]

Common Name

English

BATANOPRIDE HCL

Common Name

English

BATANOPRIDE HYDROCHLORIDE, (±)-

Common Name

English

4-AMINO-2-(BUTAN-2-ON-3-YL)OXY-5-CHLORO-N-(2-(DIETHYLAMINO)ETHYL)BENZAMIDE HYDROCHLORIDE

Common Name

English

(±)-BATANOPRIDE HYDROCHLORIDE

Common Name

English

BATANOPRIDE HYDROCHLORIDE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66885