Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H10O7 |
| Molecular Weight | 194.1394 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
InChI
InChIKey=AEMOLEFTQBMNLQ-QIUUJYRFSA-N
InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
| Molecular Formula | C6H10O7 |
| Molecular Weight | 194.1394 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen. | 2001 Feb |
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| Simultaneous, two-color fluorescence detection of total protein profiles and beta-glucuronidase activity in polyacrylamide gel. | 2001 Mar |
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| Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid. | 2001 Nov |
|
| Conformation of heparin pentasaccharide bound to antithrombin III. | 2001 Oct 15 |
|
| Oligosaccharide synthesis with glycosyl phosphate and dithiophosphate triesters as glycosylating agents. | 2001 Oct 3 |
|
| Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. | 2002 Feb |
|
| Synthesis and biological activity of the prodrug of class I major histocompatibility peptide GILGFVFTL activated by beta-glucuronidase. | 2002 Feb 14 |
|
| Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). | 2002 Feb 22 |
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| Repeated intravenous doses of all-trans-retinoyl beta-D-glucuronide is not effective in the treatment of bacterial bronchopneumonia in lambs but is devoid of gross and acute toxicity. | 2002 Sep |
|
| Interaction of heparin with internally quenched fluorogenic peptides derived from heparin-binding consensus sequences, kallistatin and anti-thrombin III. | 2002 Sep 1 |
|
| Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity. | 2002 Sep 9 |
|
| Conformational behavior of chondroitin and chondroitin sulfate in relation to their physical properties as inferred by molecular modeling. | 2003 May |
|
| The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry. | 2004 |
|
| Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats. | 2004 Apr |
|
| Structural studies of the capsular polysaccharide of a non-neoformans Cryptococcus species identified as C. laurentii, which was reclassified as Cryptococcus flavescens, from a patient with AIDS. | 2004 Feb 25 |
|
| Hapten-directed targeting to single-chain antibody receptors. | 2004 May |
|
| Pharmacokinetics, metabolism and excretion of intravenous [l4C]-palonosetron in healthy human volunteers. | 2004 Nov |
|
| A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. | 2005 May 23 |
|
| Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report. | 2005 Sep |
|
| Increase in hyaluronic acid production by Streptococcus equi subsp. zooepidemicus strain deficient in beta-glucuronidase in laboratory conditions. | 2006 Jul |
|
| Cytokines and proteoglycans: an introductory overview. | 2006 Jun |
|
| Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver. | 2007 Jul |
|
| Effects of monoglycerides on rhodamine 123 accumulation, estradiol 17 beta-D-glucuronide bidirectional transport and MRP2 protein expression within Caco-2 cells. | 2008 |
|
| Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol). | 2009 Sep |
|
| NMR spectroscopy evaluation of direct relationship between soils and molecular composition of red wines from Aglianico grapes. | 2010 Jul 19 |
|
| Understanding chemotherapy treatment pathways of advanced colorectal cancer patients to inform an economic evaluation in the United Kingdom. | 2010 Jul 27 |
|
| Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1. | 2010 Jun 25 |
|
| Biotransformation of fluorobiphenyl by Cunninghamella elegans. | 2010 Mar |
|
| Conformational free energies of methyl-alpha-L-iduronic and methyl-beta-D-glucuronic acids in water. | 2010 Mar 14 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 10:00:48 GMT 2023
by
admin
on
Sat Dec 16 10:00:48 GMT 2023
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| Record UNII |
00A9JB14O6
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| Record Status |
Validated (UNII)
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| Record Version |
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441478
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DTXSID801336828
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DB03156
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2569975
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00A9JB14O6
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admin on Sat Dec 16 10:00:48 GMT 2023 , Edited by admin on Sat Dec 16 10:00:48 GMT 2023
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