Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C6H10O7 |
| Molecular Weight | 194.1394 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
InChI
InChIKey=AEMOLEFTQBMNLQ-QIUUJYRFSA-N
InChI=1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
| Molecular Formula | C6H10O7 |
| Molecular Weight | 194.1394 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Understanding chemotherapy treatment pathways of advanced colorectal cancer patients to inform an economic evaluation in the United Kingdom. | 2010-07-27 |
|
| NMR spectroscopy evaluation of direct relationship between soils and molecular composition of red wines from Aglianico grapes. | 2010-07-19 |
|
| Regio- and stereospecific synthesis of mono-beta-d-glucuronic acid derivatives of combretastatin A-1. | 2010-06-25 |
|
| Conformational free energies of methyl-alpha-L-iduronic and methyl-beta-D-glucuronic acids in water. | 2010-03-14 |
|
| Biotransformation of fluorobiphenyl by Cunninghamella elegans. | 2010-03 |
|
| Conformational properties of the disaccharide building units of hyaluronan. | 2009-09-08 |
|
| Application of a key events dose-response analysis to nutrients: a case study with vitamin A (retinol). | 2009-09 |
|
| The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid. | 2009-05-12 |
|
| Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions. | 2008-07-01 |
|
| Vibrational analysis of N-acetyl-alpha-D-glucosamine and beta-D-glucuronic acid. | 2008-05-08 |
|
| Effects of monoglycerides on rhodamine 123 accumulation, estradiol 17 beta-D-glucuronide bidirectional transport and MRP2 protein expression within Caco-2 cells. | 2008 |
|
| Oral absorption enhancement of dipeptide L-Glu-L-Trp-OH by lipid and glycosyl conjugation. | 2008 |
|
| Predominant contribution of UDP-glucuronosyltransferase 2B7 in the glucuronidation of racemic flurbiprofen in the human liver. | 2007-07 |
|
| Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitment. | 2007-05-18 |
|
| Minor groove binder antibody conjugates employing a water soluble beta-glucuronide linker. | 2007-04-15 |
|
| [Identification of metabolites of environmental hormone butylbenzyl phthalate in mice urine by liquid chromatography/ion trap mass spectrometry]. | 2007-03 |
|
| Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of beta-D-glucopyranosiduronic acids promoted by SnCl(4). | 2007 |
|
| Evaluation of novel fluorogenic substrates for the detection of glycosidases in Escherichia coli and enterococci. | 2006-11 |
|
| NMR characterization of an S-linked glucuronide metabolite of the potent, novel, nonsteroidal progesterone agonist tanaproget. | 2006-08 |
|
| Increase in hyaluronic acid production by Streptococcus equi subsp. zooepidemicus strain deficient in beta-glucuronidase in laboratory conditions. | 2006-07 |
|
| Cytokines and proteoglycans: an introductory overview. | 2006-06 |
|
| Development and properties of beta-glucuronide linkers for monoclonal antibody-drug conjugates. | 2006-05-18 |
|
| Optimization of an enzymatic method for the determination of lysosomal N-acetyl-beta-D-hexosaminidase and beta-glucuronidase in synovial fluid. | 2006 |
|
| A gadolinium chelate for detection of beta-glucuronidase: a self-immolative approach. | 2005-09-21 |
|
| Irinotecan therapy in a 12-year-old girl with recurrent brain stem glioma and without functional polymorphisms in UGT1A1 activity: case report. | 2005-09 |
|
| A phase II trial of gefitinib with 5-fluorouracil, leucovorin, and irinotecan in patients with colorectal cancer. | 2005-05-23 |
|
| Discovery, biosynthesis, and structure elucidation of metabolites of a doping agent and a direct analogue, tetrahydrogestrinone and gestrinone, using human hepatocytes. | 2005-05-15 |
|
| A phase I clinical and pharmacokinetic study of capecitabine (Xeloda) and irinotecan combination therapy (XELIRI) in patients with metastatic gastrointestinal tumours. | 2005-03-14 |
|
| Distribution of small proteoglycans and glycosaminoglycans in humerus-related articular cartilage of chickens. | 2005-03 |
|
| Density functional study of the conformational space of 4C1 D-glucuronic acid. | 2005-02-10 |
|
| Clinical pharmacogenetics of irinotecan (CPT-11). | 2005 |
|
| Detection of stanozolol and its metabolites in equine urine by liquid chromatography-electrospray ionization ion trap mass spectrometry. | 2004-11-05 |
|
| Pharmacokinetics, metabolism and excretion of intravenous [l4C]-palonosetron in healthy human volunteers. | 2004-11 |
|
| Estradiol 3-glucuronide is transported by the multidrug resistance-associated protein 2 but does not activate the allosteric site bound by estradiol 17-glucuronide. | 2004-10 |
|
| Hapten-directed targeting to single-chain antibody receptors. | 2004-05 |
|
| Biopharmaceutics of beta-cyclodextrin derivative-based formulations of acitretin in Sprague-Dawley rats. | 2004-04 |
|
| Structural studies of the capsular polysaccharide of a non-neoformans Cryptococcus species identified as C. laurentii, which was reclassified as Cryptococcus flavescens, from a patient with AIDS. | 2004-02-25 |
|
| Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans. | 2004-01 |
|
| The detection of piroxicam, tenoxicam and their metabolites in equine urine by electrospray ionisation ion trap mass spectrometry. | 2004 |
|
| Gender differences in the levels of bisphenol A metabolites in urine. | 2003-12-12 |
|
| Conformational behavior of chondroitin and chondroitin sulfate in relation to their physical properties as inferred by molecular modeling. | 2003-05 |
|
| Structural features of an arabinogalactan gum exudates from Spondias dulsis (Anacardiaceae). | 2003-03-28 |
|
| gem-Diamine 1-N-iminosugars and related iminosugars, candidate of therapeutic agents for tumor metastasis. | 2003 |
|
| Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity. | 2002-09-09 |
|
| Interaction of heparin with internally quenched fluorogenic peptides derived from heparin-binding consensus sequences, kallistatin and anti-thrombin III. | 2002-09-01 |
|
| Repeated intravenous doses of all-trans-retinoyl beta-D-glucuronide is not effective in the treatment of bacterial bronchopneumonia in lambs but is devoid of gross and acute toxicity. | 2002-09 |
|
| An improved formulation of SYPRO Ruby protein gel stain: comparison with the original formulation and with a ruthenium II tris (bathophenanthroline disulfonate) formulation. | 2002-05 |
|
| Transcellular transport of organic anions across a double-transfected Madin-Darby canine kidney II cell monolayer expressing both human organic anion-transporting polypeptide (OATP2/SLC21A6) and Multidrug resistance-associated protein 2 (MRP2/ABCC2). | 2002-02-22 |
|
| Synthesis and biological activity of the prodrug of class I major histocompatibility peptide GILGFVFTL activated by beta-glucuronidase. | 2002-02-14 |
|
| Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. | 2002-02 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:58:03 GMT 2025
by
admin
on
Mon Mar 31 22:58:03 GMT 2025
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| Record UNII |
00A9JB14O6
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| Record Status |
Validated (UNII)
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| Record Version |
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DTXSID801336828
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DB03156
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2569975
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00A9JB14O6
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