U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry MIXED
Molecular Formula C21H38O4
Molecular Weight 354.524
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 4
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of RIOPROSTIL

SMILES

CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCCO

InChI

InChIKey=SPOAFZKFCYREMW-FWYLUGOYSA-N
InChI=1S/C21H38O4/c1-3-4-13-21(2,25)14-10-12-18-17(19(23)16-20(18)24)11-8-6-5-7-9-15-22/h10,12,17-18,20,22,24-25H,3-9,11,13-16H2,1-2H3/b12-10+/t17-,18-,20-,21?/m1/s1

HIDE SMILES / InChI
Rioprostil is a methylprostaglandin E1 analog. Rioprostil inhibits gastric acid secretion and enhances the gastric mucus-bicarbonate barrier. In peptic ulcer cases, it facilitates the healing process and the elimination of pain. Rioprostil can also be used to prevent recurrence of duodenal ulcers. However, its development has been discontinued in 2000.

Approval Year

Name Type Language
RIOPROSTIL
INN   MART.   MI   USAN  
USAN   INN  
Official Name English
RIOPROSTIL [MART.]
Common Name English
rioprostil [INN]
Common Name English
RWJ 15927
Code English
RIOPROSTIL [USAN]
Common Name English
RIOPROSTIL [MI]
Common Name English
ORF-15927
Code English
PROST-13-EN-9-ONE, 1,11,16-TRIHYDROXY-16-METHYL-, (11.ALPHA.,13E)-
Systematic Name English
TR-4698
Code English
(2R,3R,4R)-4-Hydroxy-2-(7-hydroxyheptyl)-3-[(E)-(4RS)-(4-hydroxy-4-methyl-1-octenyl)]cyclopentanone
Systematic Name English
RWJ-15927
Code English
ORF 15927
Code English
Classification Tree Code System Code
NCI_THESAURUS C78568
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
Code System Code Type Description
FDA UNII
7JL402PVQR
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
USAN
S-95
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
EPA CompTox
DTXSID70102162
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
DRUG CENTRAL
3529
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PRIMARY
CAS
77287-05-9
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
ChEMBL
CHEMBL3301679
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
INN
5299
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
MESH
D016630
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
SMS_ID
100000080588
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
EVMPD
SUB10327MIG
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
PUBCHEM
5311413
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
NCI_THESAURUS
C90930
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY
MERCK INDEX
m9629
Created by admin on Fri Dec 15 17:28:35 GMT 2023 , Edited by admin on Fri Dec 15 17:28:35 GMT 2023
PRIMARY Merck Index