Stereochemistry | ACHIRAL |
Molecular Formula | C15H13NO3S2 |
Molecular Weight | 319.399 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 2 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(=C/C1=CC=CC=C1)\C=C2/SC(=S)N(CC(O)=O)C2=O
InChI
InChIKey=CHNUOJQWGUIOLD-NFZZJPOKSA-N
InChI=1S/C15H13NO3S2/c1-10(7-11-5-3-2-4-6-11)8-12-14(19)16(9-13(17)18)15(20)21-12/h2-8H,9H2,1H3,(H,17,18)/b10-7+,12-8-
CNS Activity
Originator
Approval Year
PubMed
Patents
Sample Use Guides
Human umbilical vein endothelial cells were cultured for 48 h in glucose-rich (27.8 mM) medium. The increased neutrophil-endothelial cell adhesion and surface expression of intercellular adhesion molecule-1 (ICAM-1), P-selectin, and E-selectin on endothelial cells was inhibited by 10 microM of epalrestat.