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Details

Stereochemistry ACHIRAL
Molecular Formula C6H11NO2.ClH
Molecular Weight 165.618
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCLOLEUCINE HYDROCHLORIDE

SMILES

Cl.NC1(CCCC1)C(O)=O

InChI

InChIKey=ONNMHNDIUIHULO-UHFFFAOYSA-N
InChI=1S/C6H11NO2.ClH/c7-6(5(8)9)3-1-2-4-6;/h1-4,7H2,(H,8,9);1H

HIDE SMILES / InChI

Approval Year

PubMed

PubMed

TitleDatePubMed
Sustained L-type calcium currents in dissociated deep dorsal horn neurons of the rat: characteristics and modulation.
2001
Upregulation of preprodynorphin and preproenkephalin mRNA expression by selective activation of group I metabotropic glutamate receptors in characterized primary cultures of rat striatal neurons.
2001 Jan 31
Separation, identification, and quantification of amino acids in L-lysine fermentation potato juices by gas chromatography-mass spectrometry.
2001 Oct
Activation of a latent respiratory motor pathway by stimulation of neurons in the medullary chemoreceptor area of the rat.
2001 Sep
Stereoselective synthesis of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid via C-H insertion of alkylidenecarbene.
2002 Apr
The activation of metabotropic glutamate receptors differentially affects GABA and alpha-melanocyte stimulating hormone release from the hypothalamus and the posterior pituitary of male rats.
2002 Jul 19
Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro.
2002 Sep 6
Reduced activity of hippocampal group-I metabotropic glutamate receptors in learning-prone rats.
2003
Effects of a selective metabotropic glutamate receptor agonist on the micturition reflex pathway in urethane-anesthetized rats.
2003
Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area.
2003
Functional synaptic contacts by intranuclear axon collaterals of thalamic relay neurons.
2003 Aug 20
The use of enantiomerically pure ketene dithioacetal bis(sulfoxides) in highly diastereoselective intramolecular nitrone cycloadditions. Application in the total synthesis of the beta-amino acid (-)-cispentacin and the first asymmetric synthesis of cis-(3R,4R)-4-amino-pyrrolidine-3-carboxylic acid.
2003 Feb 21
Enhancement of low-voltage-activated calcium currents by group II metabotropic glutamate receptors in rat retinal ganglion cells.
2003 Jul
Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold.
2003 Jul 16
Endogenous zinc as a retinal neuromodulator: evidence from the skate (Raja erinacea).
2003 Jul 17
Characterisation of methionine adenosyltransferase from Mycobacterium smegmatis and M. tuberculosis.
2003 Jun 16
Alpha-cycloPNA: 1-aminocylopentane-1-carboxylic acid-derived peptide nucleic acid.
2003 May-Aug
Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retina.
2003 May-Jun
Assessment of treatment response by autoradiography with (14)C-aminocyclopentane carboxylic acid, (67)Ga-DTPA, and (18)F-FDG in a herpes simplex virus thymidine kinase/ganciclovir brain tumor model.
2003 Nov
Metabotropic glutamate receptors (mGluRs) are involved in early phase of memory formation: possible role of modulation of glutamate release.
2003 Sep-Oct
NMDA receptors in nucleus tractus solitarii are linked to soluble guanylate cyclase.
2004 Apr
Expression and functional properties of group I metabotropic glutamate receptors in bovine chromaffin cells.
2004 Jan 15
Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides.
2004 Jan 16
S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S).
2004 Jul
NMDA receptor antagonism blocks the cardiovascular responses to microinjection of trans-ACPD into the NTS of awake rats.
2004 May
Patents
Name Type Language
CYCLOLEUCINE HYDROCHLORIDE
MI  
Common Name English
CYCLOPENTANECARBOXYLIC ACID, 1-AMINO-, HYDROCHLORIDE
Common Name English
CYCLOPENTANECARBOXYLIC ACID, 1-AMINO-, HYDROCHLORIDE (1:1)
Common Name English
CYCLOLEUCINE HYDROCHLORIDE [MI]
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID30238990
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY
PUBCHEM
3021985
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY
DRUG BANK
DBSALT002211
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY
CAS
92398-48-6
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY
FDA UNII
Z72HVF4L7V
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY
MERCK INDEX
m3997
Created by admin on Sat Dec 16 04:17:28 GMT 2023 , Edited by admin on Sat Dec 16 04:17:28 GMT 2023
PRIMARY Merck Index