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Details

Stereochemistry ABSOLUTE
Molecular Formula C22H30N2O6.ClH
Molecular Weight 454.944
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ZD-7114 HYDROCHLORIDE

SMILES

Cl.COCCNC(=O)COC1=CC=C(OCCNC[C@H](O)COC2=CC=CC=C2)C=C1

InChI

InChIKey=KCAMZVQSGDBGGF-FERBBOLQSA-N
InChI=1S/C22H30N2O6.ClH/c1-27-13-12-24-22(26)17-30-21-9-7-20(8-10-21)28-14-11-23-15-18(25)16-29-19-5-3-2-4-6-19;/h2-10,18,23,25H,11-17H2,1H3,(H,24,26);1H/t18-;/m0./s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
1.9 nM [EC50]
PubMed

PubMed

TitleDatePubMed
Evaluation of ICI D7114, a putative stimulant of brown adipocytes, on histamine-contracted guinea-pig ileum.
1993 Aug
Effects of ZD7114, a selective beta3-adrenoceptor agonist, on neuroendocrine mechanisms controlling energy balance.
1998 Apr 24
Gastroprotective effect of beta3 adrenoreceptor agonists ZD 7114 and CGP 12177A in rats.
2002 Oct
Name Type Language
ZD-7114 HYDROCHLORIDE
Code English
ACETAMIDE, 2-(4-(2-((2-HYDROXY-3-PHENOXYPROPYL)AMINO)ETHOXY)PHENOXY)-N-(2-METHOXYETHYL)-, MONOHYDROCHLORIDE, (S)-
Systematic Name English
D-7114 HYDROCHLORIDE
Common Name English
Code System Code Type Description
CAS
129689-28-7
Created by admin on Tue Oct 22 12:35:26 UTC 2019 , Edited by admin on Tue Oct 22 12:35:26 UTC 2019
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