UNC-0646

Details

Stereochemistry	ACHIRAL
Molecular Formula	C36H59N7O2
Molecular Weight	621.8994
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC2=C(NC3CCN(CC3)C4CCCCC4)N=C(N=C2C=C1OCCCN5CCCCC5)N6CCCN(CC6)C(C)C

InChI

InChIKey=OUKWLRHRXOPODD-UHFFFAOYSA-N

InChI=1S/C36H59N7O2/c1-28(2)41-19-10-20-43(24-23-41)36-38-32-27-34(45-25-11-18-40-16-8-5-9-17-40)33(44-3)26-31(32)35(39-36)37-29-14-21-42(22-15-29)30-12-6-4-7-13-30/h26-30H,4-25H2,1-3H3,(H,37,38,39)

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 7 Target ID: CHEMBL6032 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21780790	Inhibitor 8297		6.0 nM [IC50]
Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 5 Target ID: CHEMBL6031 Sources: https://www.ncbi.nlm.nih.gov/pubmed/21780790	Inhibitor 8297		15.0 nM [IC50]

Name

Type

Language

UNC-0646

Common Name

English

UNC0646

Common Name

English

N-(1-Cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine

Systematic Name

English

Code System Code Type Description

PUBCHEM

53315882

Created by admin on Sat Dec 16 19:36:04 GMT 2023 , Edited by admin on Sat Dec 16 19:36:04 GMT 2023

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FDA UNII

Z5F4D95Y7J

Created by admin on Sat Dec 16 19:36:04 GMT 2023 , Edited by admin on Sat Dec 16 19:36:04 GMT 2023

PRIMARY

CAS

1320288-17-2

Created by admin on Sat Dec 16 19:36:04 GMT 2023 , Edited by admin on Sat Dec 16 19:36:04 GMT 2023

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ACTIVE MOIETY


					Z5F4D95Y7J

UNC-0646