Oxiniacic Acid

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H5NO3
Molecular Weight	139.1088
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of Oxiniacic Acid

Structure Search

SMILES

OC(=O)C1=CC=C[N+]([O-])=C1

InChI

InChIKey=FJCFFCXMEXZEIM-UHFFFAOYSA-N

InChI=1S/C6H5NO3/c8-6(9)5-2-1-3-7(10)4-5/h1-4H,(H,8,9)

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3707598

Oxiniacic Acid is a nicotinic acid derivative, that shows potent hypolipidemic activity.

Originator

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Microsomal glutathione S-transferase 1 1 Target ID: CHEMBL1743184 Sources: https://www.ncbi.nlm.nih.gov/pubmed/3707598	Inhibitor 8297

Conditions

Conditions

Condition	Modality	Targets	Highest Phase	Product
Hyperlipidemia 80 Sources: https://www.ncbi.nlm.nih.gov/pubmed/607948	Primary		Basic research	Unknown Approved Use Unknown

PubMed

PubMed

Title	Date	PubMed
Inhibition of liver glutathione S-transferase activity in rats by hypolipidemic drugs related or unrelated to clofibrate.	1986 May 15	3707598

Patents

Patents

Sample Use Guides

In Vivo Use Guide

Rats were given a daily i.p. injection for 10 days of ethanolamine oxiniacate (500 mg/kg).

Route of Administration: Intraperitoneal

In Vitro Use Guide

Unknown

Name

Type

Language

Oxiniacic Acid

Official Name

English

OXINIACIC ACID [MI]

Common Name

English

3-Pyridinecarboxylic acid, 1-oxide

Systematic Name

English

Nicotinic acid, 1-oxide

Systematic Name

English

oxiniacic acid [INN]

Common Name

English

Nicotinic acid N-oxide

Systematic Name

English

NSC-93890

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C345

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NCI_THESAURUS

C98151

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Code System Code Type Description

PUBCHEM

16976

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MERCK INDEX

m8310

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Merck Index

WIKIPEDIA

Nicotinic acid N-oxide

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SMS_ID

100000083065

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DRUG CENTRAL

3410

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NCI_THESAURUS

C66269

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CAS

2398-81-4

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ChEMBL

CHEMBL1591725

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ECHA (EC/EINECS)

219-265-0

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EPA CompTox

DTXSID2046543

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NSC

93890

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EVMPD

SUB09533MIG

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FDA UNII

YY03Q39E6L

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INN

2768

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ACTIVE MOIETY


					YY03Q39E6L