Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H28O6 |
| Molecular Weight | 376.4434 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 0 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(CCC(O)CC(O)CCC2=CC(OC)=C(O)C=C2)=CC=C1O
InChI
InChIKey=OELMAFBLFOKZJD-UHFFFAOYSA-N
InChI=1S/C21H28O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,16-17,22-25H,3-4,7-8,13H2,1-2H3
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Comparative studies on the suppression of nitric oxide synthase by curcumin and its hydrogenated metabolites through down-regulation of IkappaB kinase and NFkappaB activation in macrophages. | 2000 Dec 1 |
|
| Microbial conversion of curcumin into colorless hydroderivatives by the endophytic fungus Diaporthe sp. associated with Curcuma longa. | 2011 |
|
| Curcumin's Metabolites, Tetrahydrocurcumin and Octahydrocurcumin, Possess Superior Anti-inflammatory Effects in vivo Through Suppression of TAK1-NF-κB Pathway. | 2018 |
|
| Development of Validated Methods and Quantification of Curcuminoids and Curcumin Metabolites and Their Pharmacokinetic Study of Oral Administration of Complete Natural Turmeric Formulation (Cureit™) in Human Plasma via UPLC/ESI-Q-TOF-MS Spectrometry. | 2018 Sep 20 |
|
| Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway. | 2019 Jan |
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36062-07-4
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DTXSID40873750
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YS2A8X6SX2
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11068834
Created by
admin on Sat Dec 16 11:23:57 GMT 2023 , Edited by admin on Sat Dec 16 11:23:57 GMT 2023
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PARENT (METABOLITE)
SUBSTANCE RECORD
