U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry RACEMIC
Molecular Formula C19H16N2O4
Molecular Weight 336.3413
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENZOBARBITAL

SMILES

CCC1(C(=O)NC(=O)N(C(=O)C2=CC=CC=C2)C1=O)C3=CC=CC=C3

InChI

InChIKey=QMOWPJIFTHVQMB-UHFFFAOYSA-N
InChI=1S/C19H16N2O4/c1-2-19(14-11-7-4-8-12-14)16(23)20-18(25)21(17(19)24)15(22)13-9-5-3-6-10-13/h3-12H,2H2,1H3,(H,20,23,25)

HIDE SMILES / InChI
Benzobarbital (under the brand name Benzona), a barbiturate derivative developed in Russia that is used to treat convulsive forms of epilepsy, newborn hemolytic disease, and insomnia.

Approval Year

PubMed

PubMed

TitleDatePubMed
[A comparative study of efferent methods of treatment and bezonal on the absorptive and excretory liver function in patients with acute diffuse peritonitis].
2002
[Liver monooxygenase system inducers in the treatment of respiratory distress syndrome in newborn].
2002 Mar
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
2004
[The effect of Asian cobra venom on the content of rat heart and liver mitochondrial phospholipids and the protective effect of benzonal].
2005 Sep-Oct
[Analysis of blood hormone levels in boys of prepubertal and pubertal age with epilepsy treated with different antiepileptic drugs].
2008

Sample Use Guides

In Vivo Use Guide
For adults: 0.1 g 3 times a day (the highest daily dose is 0.8 g), for children (3 times a day): 3–6 years - 0.025–0.05 g, 7–10 years - 0, 05–0.1 g, 11–14 years old - 0.1 g (the highest daily is 0.45 g);
Route of Administration: Oral
Name Type Language
BENZOBARBITAL
INN   MART.   WHO-DD  
INN  
Official Name English
Benzobarbital [WHO-DD]
Common Name English
BENZOBARBITAL [MART.]
Common Name English
benzobarbital [INN]
Common Name English
1-BENZOYL-5-ETHYL-5-PHENYLBARBITURIC ACID
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C67084
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
Code System Code Type Description
PUBCHEM
12938
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
PRIMARY
SMS_ID
100000086367
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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ChEMBL
CHEMBL1338506
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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EVMPD
SUB05754MIG
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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CAS
744-80-9
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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NCI_THESAURUS
C77628
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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EPA CompTox
DTXSID1046138
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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MESH
C002915
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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WIKIPEDIA
BENZOBARBITAL
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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INN
3082
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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FDA UNII
YNJ78BD0AH
Created by admin on Fri Dec 15 17:35:45 GMT 2023 , Edited by admin on Fri Dec 15 17:35:45 GMT 2023
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