Details
Stereochemistry | ACHIRAL |
Molecular Formula | C27H32O4 |
Molecular Weight | 420.5406 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 4 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(\C=C\C1=C(C)CCCC1(C)C)=C/C=C(/C(C)=C\C(O)=O)C2=CC(=CC=C2)C(O)=O
InChI
InChIKey=XKKDQOHDTASHCE-PAZAWXFKSA-N
InChI=1S/C27H32O4/c1-18(12-14-24-19(2)8-7-15-27(24,4)5)11-13-23(20(3)16-25(28)29)21-9-6-10-22(17-21)26(30)31/h6,9-14,16-17H,7-8,15H2,1-5H3,(H,28,29)(H,30,31)/b14-12+,18-11+,20-16-,23-13-
Originator
Approval Year
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7965805
BMS-181162 reversibly inhibited phospholipase A2 purified from human synovial fluid with an IC50 of 8 microns. In A23187-stimulated human polymorphonuclear leukocytes, BMS-181162 blocked arachidonic acid release with an IC50 of 10 microns. Leukotriene B4 biosynthesis in these cells was also inhibited.
Name | Type | Language | ||
---|---|---|---|---|
|
Common Name | English | ||
|
Code | English |
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
|
6438744
Created by
admin on Fri Dec 15 15:51:19 GMT 2023 , Edited by admin on Fri Dec 15 15:51:19 GMT 2023
|
PRIMARY | |||
|
141948-79-0
Created by
admin on Fri Dec 15 15:51:19 GMT 2023 , Edited by admin on Fri Dec 15 15:51:19 GMT 2023
|
PRIMARY | |||
|
Y8U3B6ZM8D
Created by
admin on Fri Dec 15 15:51:19 GMT 2023 , Edited by admin on Fri Dec 15 15:51:19 GMT 2023
|
PRIMARY | |||
|
DB14097
Created by
admin on Fri Dec 15 15:51:19 GMT 2023 , Edited by admin on Fri Dec 15 15:51:19 GMT 2023
|
PRIMARY |
ACTIVE MOIETY