BUNAMIDINE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H38N2O.ClH
Molecular Weight	419.043
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.CCCCCCOC1=C2C=CC=CC2=C(C=C1)C(=N)N(CCCC)CCCC

InChI

InChIKey=PBYJDHRFPFHVKZ-UHFFFAOYSA-N

InChI=1S/C25H38N2O.ClH/c1-4-7-10-13-20-28-24-17-16-23(21-14-11-12-15-22(21)24)25(26)27(18-8-5-2)19-9-6-3;/h11-12,14-17,26H,4-10,13,18-20H2,1-3H3;1H

HIDE SMILES / InChI

Description
Sources: ISBN 978-3-662-43977-7, Mehlhorn H., 'Encyclopedia of Parasitology: A-M' (2008), p. 224, Retrieved from https://books.google.com/books?id=Jpg1ysgVn-AC&dq

Bunamidine is a anti-parasitic drug, which was approved by FDA for the treatment of tapeworms in cats and dogs (Scolaban 400 tablets).

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Tapeworm infection 8 Sources: Mehlhorn H., (2008) Encyclopedia of Parasitology: A-M, page 224, retrieved from https://books.google.com/books?id=Jpg1ysgVn-AC&dq	Curative		Approved 8583	SCOLABAN 400 Approved Use The drug is intended for oral administration to dogs for the treatment of the tapeworms Dipylidium caninum, Taenia pisiformis and Echinococcus granulosus and cats for the treatment of the tapeworms Dipylidium caninum and Taenia taeniaeformis.

PubMed

Title	Date	PubMed
The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.	2004-08	15357098
The Styx Field Trial: effect of treatment of the definitive host for tapeworms on larval forms in the intermediate host.	1978	308408
Evaluation of selected drugs for the treatment of canine echinococcosis.	1968	5303842
A NEW TAENIACIDE, BUNAMIDINE HYDROCHLORIDE: ITS EFFICIENCY AGAINST TAENIA PISIFORMIS AND DIPYLIDIUM CANINUM IN THE DOG AND HYDATIGERA TAENIAEFORMIS IN THE CAT.	1965-04-10	14330224

Sample Use Guides

In Vivo Use Guide

It is administered to dogs at the rate of 25 to 50 milligrams per kilogram of body weight. The drug should be given on an empty stomach and food should not be given for 3 hours following treatment.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

BUNAMIDINE HYDROCHLORIDE

Official Name

English

NSC-106571

Preferred Name

English

BUNAMIDINE HCL

Common Name

English

BUNAMIDINE HYDROCHLORIDE [USAN]

Common Name

English

1-NAPHTHALENECARBOXIMIDAMIDE, N,N-DIBUTYL-4-(HEXYLOXY)-, MONOHYDROCHLORIDE

Common Name

English

BUNAMIDINE HYDROCHLORIDE [GREEN BOOK]

Common Name

English

N,N-Dibutyl-4-(hexyloxy)-1-naphthamidine monohydrochloride

Systematic Name

English

BUNAMIDINE HYDROCHLORIDE [MI]

Common Name

English

BUNAMIDINE HYDROCHLORIDE [MART.]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP52AX02