Details
Stereochemistry | ACHIRAL |
Molecular Formula | C16H13FN4O2 |
Molecular Weight | 312.2984 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC(NC2=NC=C(F)C(NC3=CC=CC(O)=C3)=N2)=CC=C1
InChI
InChIKey=TVKGTSHBQZEFEE-UHFFFAOYSA-N
InChI=1S/C16H13FN4O2/c17-14-9-18-16(20-11-4-2-6-13(23)8-11)21-15(14)19-10-3-1-5-12(22)7-10/h1-9,22-23H,(H2,18,19,20,21)
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: CHEMBL2599 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297 |
226.0 nM [IC50] | ||
Target ID: Leukotriene C4 production Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297 |
|||
Target ID: GO:0045576 Sources: https://www.ncbi.nlm.nih.gov/pubmed/16950297 |
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Code System | Code | Type | Description | ||
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Y7W5AL9KHB
Created by
admin on Sat Dec 16 11:14:23 GMT 2023 , Edited by admin on Sat Dec 16 11:14:23 GMT 2023
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PRIMARY | |||
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9904854
Created by
admin on Sat Dec 16 11:14:23 GMT 2023 , Edited by admin on Sat Dec 16 11:14:23 GMT 2023
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PRIMARY | |||
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R-921218
Created by
admin on Sat Dec 16 11:14:23 GMT 2023 , Edited by admin on Sat Dec 16 11:14:23 GMT 2023
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PRIMARY | This is a study of the effectiveness and safety of a new nasal spray for the relief of the symptoms of seasonal allergies. The agents being compared are: R926112 (a novel anti-allergy medicine), Beconase (beclomethasone dipropionate, an established FDA approved steroid treatment), and an inactive placebo. The study hypothesis is that R926112 will be superior to placebo at the end of a week of testing and evaluation. The study does not have the power to determine how R926112 compares to Beconase. | ||
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CHEMBL3545399
Created by
admin on Sat Dec 16 11:14:23 GMT 2023 , Edited by admin on Sat Dec 16 11:14:23 GMT 2023
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PRIMARY | |||
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575474-82-7
Created by
admin on Sat Dec 16 11:14:23 GMT 2023 , Edited by admin on Sat Dec 16 11:14:23 GMT 2023
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PRIMARY |
ACTIVE MOIETY