AS-602868

COC1=CC=CC2=NC(=NC(NN3C(=O)C=C(C)C3=O)=C12)C4=CC=CS4

InChIKey=GZGLPBNOIFLLRE-UHFFFAOYSA-N

InChI=1S/C18H14N4O3S/c1-10-9-14(23)22(18(10)24)21-17-15-11(5-3-6-12(15)25-2)19-16(20-17)13-7-4-8-26-13/h3-9H,1-2H3,(H,19,20,21)

Targets

Primary Target	Pharmacology	Condition	Potency
Inhibitor of nuclear factor kappa-B kinase subunit beta 5 Target ID: O14920 Gene ID: 3551.0 Gene Symbol: IKBKB Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/24813730	Inhibitor 8297

PubMed

Title	Date	PubMed
Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors.	2014 Jun 15	24813730

Name

Type

Language

AS-602868

Code

English

SPC-839

Code

English

1-((5-METHOXY-2-(2-THIENYL)-4-QUINAZOLINYL)AMINO)-3-METHYL-1H-PYRROLE-2,5-DIONE

Systematic Name

English

1H-PYRROLE-2,5-DIONE, 1-((5-METHOXY-2-(2-THIENYL)-4-QUINAZOLINYL)AMINO)-3-METHYL-

Systematic Name

English

Code System Code Type Description

FDA UNII

Y1FZ8P93E0