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Details

Stereochemistry MIXED
Molecular Formula C13H18N2
Molecular Weight 202.2954
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DICARBINE

SMILES

CN1CCC2NC3=CC=C(C)C=C3C2C1

InChI

InChIKey=CYJQCYXRNNCURD-UHFFFAOYSA-N
InChI=1S/C13H18N2/c1-9-3-4-12-10(7-9)11-8-15(2)6-5-13(11)14-12/h3-4,7,11,13-14H,5-6,8H2,1-2H3

HIDE SMILES / InChI

Description

Dicarbine is an orally active drug approved in Russia under the trade name Карбидин, is used for the treatment patients with schizophrenia and alcoholic psychosis. This drug blocks dopamine receptors in various brain parts, which leads to a reduction in the productive symptoms of psychosis: delusions and hallucinations.

CNS Activity

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Unknown
Primary
Unknown

PubMed

Sample Use Guides

In Vivo Use Guide
oral: schizophrenia: for adults: the initial dose of 12.5 mg to 50-75 mg, in some cases up to 400-600 mg/ day in 3 admissions. oral: alcoholic psychosis: 50 mg 3-4 times/day, intervals of 2 hours.
Route of Administration: Other
In Vitro Use Guide
Unknown