Details
Stereochemistry | ABSOLUTE |
Molecular Formula | C28H48OSe |
Molecular Weight | 475.6026 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 8 / 8 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@@]1(CC[C@@]2([H])[C@]3([H])C[C@@H](C[75Se]C)C4=C(CC[C@H](O)C4)[C@@]3([H])CC[C@]12C)[C@H](C)CCCC(C)C
InChI
InChIKey=AEVGUKVBCBHBNF-MJMUOCKJSA-N
InChI=1S/C28H48OSe/c1-18(2)7-6-8-19(3)26-11-12-27-25-15-20(17-30-5)24-16-21(29)9-10-22(24)23(25)13-14-28(26,27)4/h18-21,23,25-27,29H,6-17H2,1-5H3/t19-,20+,21+,23-,25-,26-,27+,28-/m1/s1/i30-4
Se-75 norcholesterol is radiopharmaceutical derivative of cholesterol, a natural precursor in the synthesis of adrenocortical steroid hormones. Se-75 is a radioactive isotope of selenium, it has half-life period of 120 days, and emits gamma-rays upon decay. Se-75 norcholesterol was used under tradename Scintadren to diagnose a wide range of adrenal pathologies, including Cushing syndrome, Cushing's disease, carcinoma, adrenal insufficiency, and phaeochromocytoma. The drug was withdrawn in the early 2000s in favor of I-131 norcholesterol.
Approval Year
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Classification Tree | Code System | Code | ||
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WHO-VATC |
QV09XX03
Created by
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WHO-ATC |
V09XX03
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admin on Sat Dec 16 08:04:22 GMT 2023 , Edited by admin on Sat Dec 16 08:04:22 GMT 2023
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63795-61-9
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SUB15212MIG
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100000078404
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DB13622
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122051
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72521-77-8
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admin on Sat Dec 16 08:04:22 GMT 2023 , Edited by admin on Sat Dec 16 08:04:22 GMT 2023
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DTXSID30980361
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XWR21TJ99H
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admin on Sat Dec 16 08:04:22 GMT 2023 , Edited by admin on Sat Dec 16 08:04:22 GMT 2023
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ACTIVE MOIETY