U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H5NO
Molecular Weight 59.0672
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-METHYLFORMAMIDE

SMILES

CNC=O

InChI

InChIKey=ATHHXGZTWNVVOU-UHFFFAOYSA-N
InChI=1S/C2H5NO/c1-3-2-4/h2H,1H3,(H,3,4)

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Characterization of DNA fragmentation events caused by genotoxic and non-genotoxic agents.
2001 Feb 20
Causal relationship between a case of severe hepatic dysfunction and low exposure concentrations of N,N-dimethylformamide in the synthetics industry.
2001 Jan
Evaluation of norbornene- beta-cyclodextrin-based monomers and oligomers as chiral selectors by means of nonaqueous capillary electrophoresis.
2001 Jan
Solvent effects on oxygen-17 chemical shifts in methyl formate: linear solvation shift relationships.
2001 Jan
H-bonding in liquid N-methylformamide as studied by X-ray scattering.
2002 Aug
The effect of kaolinite intercalation on the structural arrangements of N-methylformamide and 1-methyl-2-pyrrolidone.
2002 Nov 15
Analysis of metabolites of N,N-dimethylformamide in urine samples.
2004 Aug
[N-methylformamide in urine].
2004 Dec
Preferential solvation of Brooker's merocyanine in binary solvent mixtures composed of formamides and hydroxylic solvents.
2004 Mar
Evaluation of alternative cryoprotectants for preserving stallion spermatozoa.
2004 Sep 15
Solvation properties of N-substituted cis and trans amides are not identical: significant enthalpy and entropy changes are revealed by the use of variable temperature 1H NMR in aqueous and chloroform solutions and ab initio calculations.
2005 Dec 29
Simultaneous determination of N-hydroxymethyl-N-methylformamide, N-methylformamide and N-acetyl-S-(N-methylcarbamoyl)cystein in urine samples from workers exposed to N,N-dimethylformamide by liquid chromatography-tandem mass spectrometry.
2005 Feb 7
Neutron scattering study of the H-bond network in amorphous N-methylformamide.
2005 Feb 8
The role of charge transfer in the hydrogen bond cooperative effect of cis-N-methylformamide oligomers.
2005 Jul 21
Poly[bis(N-methylformamide)tetra-mu-thiocyanato-manganese(II)mercury(II)].
2005 Jun
The effects of simultaneous exposure to methyl ethyl ketone and toluene on urinary biomarkers of occupational N,N-dimethylformamide exposure.
2005 Mar 15
Improvement of stallion semen post-thaw motility with the association dimethyl formamide and methyl formamide as cryoprotectors.
2005 Oct
N-methylformamide and 9-hydroxystearic acid: two anti-proliferative and differentiating agents with different modes of action in colon cancer cells.
2006 Jun
Density functional theory study of self-association of N-methylformamide and its effect on intramolecular and intermolecular geometrical parameters and the cis/trans population.
2006 Jun 21
Effect of ozone on nicotine desorption from model surfaces: evidence for heterogeneous chemistry.
2006 Mar 15
Identification of potential genomic biomarkers of hepatotoxicity caused by reactive metabolites of N-methylformamide: Application of stable isotope labeled compounds in toxicogenomic studies.
2006 Oct
Separation of chelating agents as copper complexes by capillary zone electrophoresis using quaternary ammonium bromides as additives in N-methylformamide.
2006 Oct 27
Combining novel strategy with kinetic approach in the determination of respective respiration and skin exposure to N,N-dimethylformamide vapor.
2007 Dec 15
Separation of oligonucleotides in N-methyl-formamide-based polymer matrices by capillary electrophoresis.
2007 Jan
Patents
Name Type Language
N-METHYLFORMAMIDE
HSDB   MI  
Systematic Name English
NSC-3051
Code English
N-METHYL-FORMAMIDE
Systematic Name English
N-METHYLFORMAMIDE [HSDB]
Common Name English
NMF
Code English
N-METHYLFORMAMIDE [MI]
Common Name English
METHYLFORMAMIDE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C798
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
NCI_THESAURUS C1934
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
Code System Code Type Description
PUBCHEM
31254
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
HSDB
100
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
NSC
3051
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
ECHA (EC/EINECS)
204-624-6
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
MERCK INDEX
m7417
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY Merck Index
FDA UNII
XPE4G7Y986
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
NCI_THESAURUS
C1163
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID0025608
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
CAS
123-39-7
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
MESH
C002950
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
CHEBI
7438
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY
WIKIPEDIA
N-METHYLFORMAMIDE
Created by admin on Fri Dec 15 15:16:47 GMT 2023 , Edited by admin on Fri Dec 15 15:16:47 GMT 2023
PRIMARY