Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C23H39ClO5 |
| Molecular Weight | 431.006 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 5 / 5 |
| E/Z Centers | 1 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)OC(=O)COC\C=C/C[C@H]1[C@H](Cl)C[C@@H](O)[C@@H]1CC[C@@H](O)C2CCCCC2
InChI
InChIKey=GXLUEHGRKZQLOO-QMAHXAMHSA-N
InChI=1S/C23H39ClO5/c1-16(2)29-23(27)15-28-13-7-6-10-18-19(22(26)14-20(18)24)11-12-21(25)17-8-4-3-5-9-17/h6-7,16-22,25-26H,3-5,8-15H2,1-2H3/b7-6-/t18-,19-,20-,21-,22-/m1/s1
Approval Year
| Name | Type | Language | ||
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Code | English | ||
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Systematic Name | English | ||
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Systematic Name | English | ||
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Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
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XE6G6DQ45F
Created by
admin on Fri Dec 15 15:37:26 GMT 2023 , Edited by admin on Fri Dec 15 15:37:26 GMT 2023
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PRIMARY | |||
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AL-6598
Created by
admin on Fri Dec 15 15:37:26 GMT 2023 , Edited by admin on Fri Dec 15 15:37:26 GMT 2023
|
PRIMARY | Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2.ALPHA. and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 undefined M and demonstrates an EC50 value of 0.80 undefinedM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 undefinedg dose given twice daily. | ||
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9832594
Created by
admin on Fri Dec 15 15:37:26 GMT 2023 , Edited by admin on Fri Dec 15 15:37:26 GMT 2023
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PRIMARY | |||
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170291-06-2
Created by
admin on Fri Dec 15 15:37:26 GMT 2023 , Edited by admin on Fri Dec 15 15:37:26 GMT 2023
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PRIMARY |
ACTIVE MOIETY
