U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C21H29NO
Molecular Weight 311.4611
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ALPHAMETHADOL

SMILES

CC[C@@H](O)C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChIKey=QIRAYNIFEOXSPW-YLJYHZDGSA-N
InChI=1S/C21H29NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17,20,23H,5,16H2,1-4H3/t17-,20-/m1/s1

HIDE SMILES / InChI
Alphamethadol is a synthetic opioid analgesic. Alphamethadol is composed of two isomers itself, L-α-methadol, and D-α-methadol. L-α-methadol is an important active metabolite of levacetylmethadol (LAAM), a medication therapy for individuals addicted to opiates that provides an alternative to methadone. Isomers of Alphamethadol bind to and activate the μ-opioid receptor; they are active as opioid analgesics.

Approval Year

PubMed

PubMed

TitleDatePubMed
Name Type Language
ALPHAMETHADOL
INN  
INN  
Official Name English
IDS-NA-010
Code English
ACSCN-9605
Common Name English
.ALPHA.-6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEPTANOL
Systematic Name English
alphamethadol [INN]
Common Name English
(3R,6R)-6-DIMETHYLAMINO-4,4-DIPHENYL-3-HEPTANOL
Systematic Name English
Classification Tree Code System Code
DEA NO. 9605
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
NCI_THESAURUS C241
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
Code System Code Type Description
WIKIPEDIA
ALPHAMETHADOL
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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DRUG BANK
DB01498
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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PUBCHEM
62709
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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INN
352
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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EVMPD
SUB05365MIG
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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CAS
17199-54-1
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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SMS_ID
100000087450
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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FDA UNII
XBD99QNI42
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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EPA CompTox
DTXSID60872467
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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ChEMBL
CHEMBL159660
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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NCI_THESAURUS
C72135
Created by admin on Fri Dec 15 16:06:05 GMT 2023 , Edited by admin on Fri Dec 15 16:06:05 GMT 2023
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