Details
Stereochemistry | RACEMIC |
Molecular Formula | C23H30O6 |
Molecular Weight | 402.4807 |
Optical Activity | ( + / - ) |
Defined Stereocenters | 5 / 5 |
E/Z Centers | 3 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
COC(=O)CCC=C=CC[C@@H]1[C@H](O)C[C@H](O)[C@H]1\C=C\[C@H](O)COC2=CC=CC=C2
InChI
InChIKey=BYNHBQROLKAEDQ-CNDPCGPLSA-N
InChI=1S/C23H30O6/c1-28-23(27)12-8-3-2-7-11-19-20(22(26)15-21(19)25)14-13-17(24)16-29-18-9-5-4-6-10-18/h3-7,9-10,13-14,17,19-22,24-26H,8,11-12,15-16H2,1H3/b14-13+/t2?,17-,19-,20-,21+,22-/m0/s1
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P43118 Gene ID: 25652.0 Gene Symbol: Ptgfr Target Organism: Rattus norvegicus (Rat) Sources: https://www.ncbi.nlm.nih.gov/pubmed/3134971 |
7.4 null [pEC50] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Preventing | Porcilene Approved UseFenprostalene is indicated for use in feedlot heifers to induce abortion when pregnant 150 days or less, for the induction of parturition in sows and gilts pregnant at least 112 days. Launch Date1988 |
Sample Use Guides
In Vivo Use Guide
Sources: https://www.law.cornell.edu/cfr/text/21/522.914
(1)Cattle -
(i)Indications for use and amount - (A) For feedlot heifers to induce abortion when pregnant 150 days or less, administer 1 mg (2 milliliter (mL)) subcutaneously.
(B) For beef or nonlactating dairy cattle for estrus synchronization, administer a single or two 1-mg (2-mL) doses subcutaneously, 11 to 13 days apart. (2)Swine -
(i)Amount. Administer a single injection of 0.25 mg (1 mL) subcutaneously.
(ii)Indications for use. For the induction of parturition in sows and gilts pregnant at least 112 days.
Route of Administration:
Other
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3134971
Fenprostalene elicited contractions of the guinea-pig oesophageal muscular
mucosae with -log EC50 6.73. Fenprostalene was tested between 1 x 10(-1) and 3 x 10(-5) M.
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WHO-VATC |
QG02AD92
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CFR |
21 CFR 556.277
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CFR |
21 CFR 522.914
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NCI_THESAURUS |
C78568
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m5293
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C76898
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ACTIVE MOIETY