U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C30H33N5O2
Molecular Weight 495.6153
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Ezobresib

SMILES

CN1N=NC(C)=C1C2=CN=C3C(=C2)N([C@@H](C4CCOCC4)C5=CC=CC=C5)C6=C3C=CC(=C6)C(C)(C)O

InChI

InChIKey=KGERZPVQIRYWRK-GDLZYMKVSA-N
InChI=1S/C30H33N5O2/c1-19-28(34(4)33-32-19)22-16-26-27(31-18-22)24-11-10-23(30(2,3)36)17-25(24)35(26)29(20-8-6-5-7-9-20)21-12-14-37-15-13-21/h5-11,16-18,21,29,36H,12-15H2,1-4H3/t29-/m1/s1

HIDE SMILES / InChI

Approval Year

Patents

Patents

Name Type Language
Ezobresib
USAN  
Official Name English
BET INHIBITOR BMS-986158
Common Name English
5H-Pyrido[3,2-b]indole-7-methanol, 3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-a,a-dimethyl-5-[(S)-phenyl(tetrahydro-2H-pyran-4-yl)methyl]-
Systematic Name English
2-{3-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-7-yl}propan-2-ol
Systematic Name English
BMS-986158
Code English
EZOBRESIB [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C128462
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C121849
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
EVMPD
SUB197793
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
USAN
LM-31
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
FDA UNII
X8BW0MQ5PI
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
CAS
1800340-40-2
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
PUBCHEM
118196485
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
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INN
12855
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
DRUG BANK
DB15435
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY
SMS_ID
100000183331
Created by admin on Sat Dec 16 14:48:27 GMT 2023 , Edited by admin on Sat Dec 16 14:48:27 GMT 2023
PRIMARY