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Details

Stereochemistry ABSOLUTE
Molecular Formula C11H11NO4
Molecular Weight 221.2093
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PIDOBENZONE

SMILES

OC1=CC=C(OC(=O)[C@@H]2CCC(=O)N2)C=C1

InChI

InChIKey=SDJPNDMWNUPUFI-VIFPVBQESA-N
InChI=1S/C11H11NO4/c13-7-1-3-8(4-2-7)16-11(15)9-5-6-10(14)12-9/h1-4,9,13H,5-6H2,(H,12,14)/t9-/m0/s1

HIDE SMILES / InChI

Description

Pidobenzone, an amino acid ester of hydroquinone, is a second-generation worldwide patented depigmenting agent, reliable and free of collateral risks. Pidobenzone 4% lipogel represents a useful, reliable, and safe treatment of the different types of melasma. No data are available regarding the efficacy of pidobenzone as monotherapy for solar lentigines. The combination of cryotherapy and pidobenzone 4% has been found to be the most useful treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia.

Approval Year

PubMed

Patents

Sample Use Guides

In Vivo Use Guide
4% (K5® lipogel), twice per day for 16 weeks
Route of Administration: Topical