PIDOBENZONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C11H11NO4
Molecular Weight	221.2093
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(OC(=O)[C@@H]2CCC(=O)N2)C=C1

InChI

InChIKey=SDJPNDMWNUPUFI-VIFPVBQESA-N

InChI=1S/C11H11NO4/c13-7-1-3-8(4-2-7)16-11(15)9-5-6-10(14)12-9/h1-4,9,13H,5-6H2,(H,12,14)/t9-/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/27513344 | https://www.ncbi.nlm.nih.gov/pubmed/18727811 | DOI: 10.1007/978-3-540-71095-0_7973

Pidobenzone, an amino acid ester of hydroquinone, is a second-generation worldwide patented depigmenting agent, reliable and free of collateral risks. Pidobenzone 4% lipogel represents a useful, reliable, and safe treatment of the different types of melasma. No data are available regarding the efficacy of pidobenzone as monotherapy for solar lentigines. The combination of cryotherapy and pidobenzone 4% has been found to be the most useful treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia.

Approval Year

PubMed

Title	Date	PubMed
Melasma: successful treatment with pidobenzone 4% (K5lipogel).	2008 Jul	18727811
Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial.	2016	27513344

Patents

Sample Use Guides

In Vivo Use Guide

4% (K5® lipogel), twice per day for 16 weeks

Route of Administration: Topical

Name

Type

Language

PIDOBENZONE

Official Name

English

pidobenzone [INN]

Common Name

English

PIDOBENZONE [INCI]

Common Name

English

5-OXO-L-PROLINE,P-HYDROXYPHENYL ESTER

Common Name

English

Pidobenzone [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78284