CP-373420

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H21N3O4
Molecular Weight	379.4091
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COCCOC1=CC2=C(C=C1OCCO)C(NC3=CC(=CC=C3)C#C)=NC=N2

InChI

InChIKey=KOQIAZNBAWFSQM-UHFFFAOYSA-N

InChI=1S/C21H21N3O4/c1-3-15-5-4-6-16(11-15)24-21-17-12-19(27-8-7-25)20(28-10-9-26-2)13-18(17)22-14-23-21/h1,4-6,11-14,25H,7-10H2,2H3,(H,22,23,24)

HIDE SMILES / InChI

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Epidermal growth factor receptor 46 Target ID: P00533\|\|\|Q9GZX1 Gene ID: 1956.0 Gene Symbol: EGFR Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/16381666 \| https://www.ncbi.nlm.nih.gov/pubmed/9354447	Inhibitor 8297

Name

Type

Language

CP-373420

Common Name

English

OSI-420

Common Name

English

ETHANOL, 2-((4-((3-ETHYNYLPHENYL)AMINO)-7-(2-METHOXYETHOXY)-6-QUINAZOLINYL)OXY)-

Systematic Name

English

2-(4-(3-ETHYNYLANILINO)-7-(2-METHOXYETHOXY)QUINAZOLIN-6-YL)OXYETHANOL

Systematic Name

English

ERLOTINIB METABOLITE M14

Common Name

English

Code System Code Type Description

PUBCHEM

10317566

Created by admin on Sat Dec 16 09:27:40 GMT 2023 , Edited by admin on Sat Dec 16 09:27:40 GMT 2023

PRIMARY

FDA UNII

X78J9Z28DQ

Created by admin on Sat Dec 16 09:27:40 GMT 2023 , Edited by admin on Sat Dec 16 09:27:40 GMT 2023

PRIMARY

CAS

183321-86-0

Created by admin on Sat Dec 16 09:27:40 GMT 2023 , Edited by admin on Sat Dec 16 09:27:40 GMT 2023

PRIMARY

EPA CompTox

DTXSID10939711

Created by admin on Sat Dec 16 09:27:40 GMT 2023 , Edited by admin on Sat Dec 16 09:27:40 GMT 2023

PRIMARY

PARENT (METABOLITE ACTIVE)


					J4T82NDH7E

ERLOTINIB

SALT/SOLVATE (PARENT)


					ZJ7FA2S8Q6

Desmethyl Erlotinib

SUBSTANCE RECORD


					X78J9Z28DQ

CP-373420