FENIPENTOL

Details

Stereochemistry	RACEMIC
Molecular Formula	C11H16O
Molecular Weight	164.2441
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC(O)C1=CC=CC=C1

InChI

InChIKey=OVGORFFCBUIFIA-UHFFFAOYSA-N

InChI=1S/C11H16O/c1-2-3-9-11(12)10-7-5-4-6-8-10/h4-8,11-12H,2-3,9H2,1H3

HIDE SMILES / InChI

Description
Sources: http://www.noventis.cz/febichol-gp

Fenipentol is a choleretic agent indicated for the treatment of chronic liver disease and bile duct disease. The drug is sold without prescription.

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Secretion of bile 1 Target ID: Secretion of bile Sources: http://www.ncbi.nlm.nih.gov/pubmed/13924674	Activator 1430

Conditions

Condition	Modality	Targets	Highest Phase	Product
Chronic liver disease 2 Sources: http://www.noventis.cz/febichol-gp	Primary		Approved 8429	FEBICHOL Approved Use Febichol capsules are to be used by adult patients to treat digestive problems in chronic (long-term) liver disease and bile duct disease (disorders of gall bladder activity, chronic cholecystitis, chronic development of gall bladder stones, chronic liver disease associated with digestive symptoms caused by impairment or disorder of biliary tree) and conditions after surgical removal of gall bladder or after hepatitis.
Bile duct disease 1 Sources: http://www.noventis.cz/febichol-gp	Primary		Approved 8429	FEBICHOL Approved Use Febichol capsules are to be used by adult patients to treat digestive problems in chronic (long-term) liver disease and bile duct disease (disorders of gall bladder activity, chronic cholecystitis, chronic development of gall bladder stones, chronic liver disease associated with digestive symptoms caused by impairment or disorder of biliary tree) and conditions after surgical removal of gall bladder or after hepatitis.

PubMed

Title	Date	PubMed
Synthesis and antioxidant properties of some indole ethylamine derivatives as melatonin analogs.	2005 Sep	16222860
Running speed in mammals increases with muscle n-6 polyunsaturated fatty acid content.	2006 Dec 20	17183696
Dietary exposure of children and teenagers to benzoates, sulphites, butylhydroxyanisol (BHA) and butylhydroxytoluen (BHT) in Beirut (Lebanon).	2007 Feb	16996185
Improved and efficient synthesis of chiral N,P-ligands via cyclic sulfamidates for asymmetric addition of butyllithium to benzaldehyde.	2007 Sep 13	17696545
Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism.	2008 Nov 28	19040724
Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits.	2010 Dec	20696249
Contribution of dietary intakes of antioxidants to homocysteine-induced low density lipoprotein (LDL) oxidation in atherosclerotic patients.	2010 Jul	20499417

Patents

Sample Use Guides

In Vivo Use Guide

Standard dosage for adults and youths over 15 years of age is 2 capsules (each capsule of contains 100 mg of active ingredient fenipentol) three times a day (always immediately before meals).

Route of Administration: Oral

In Vitro Use Guide

Unknown

Name

Type

Language

FENIPENTOL

Official Name

English

BENZYL ALCOHOL, .ALPHA.-BUTYL-

Systematic Name

English

PHENYLBUTYLCARBINOL

Systematic Name

English

FENIPENTOL [JAN]

Common Name

English

FENIPENTOL [MART.]

Common Name

English

FENIPENTOL [MI]

Common Name

English

1-PHENYL-1-HYDROXY-N-PENTANE

Common Name

English

(±)-.ALPHA.-BUTYLBENZYL ALCOHOL

Systematic Name

English

PH-BC

Code

English

1-PHENYL-1-HYDROXYPENTANE

Systematic Name

English

fenipentol [INN]

Common Name

English

(±)-1-PHENYL-1-PENTANOL

Systematic Name

English

PC-1

Code

English

NSC-8478

Code

English

PANCORAL

Brand Name

English

1-PENTANOL, 1-PHENYL-

Systematic Name

English

Fenipentol [WHO-DD]

Common Name

English

.ALPHA.-BUTYLBENZYL ALCOHOL

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66913