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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H31NO4S
Molecular Weight 429.572
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABIRATERONE SULFATE

SMILES

[H][C@@]12CC=C(C3=CC=CN=C3)[C@@]1(C)CC[C@@]4([H])[C@@]2([H])CC=C5C[C@H](CC[C@]45C)OS(O)(=O)=O

InChI

InChIKey=LUQSJWRTYLGZJB-VJLLXTKPSA-N
InChI=1S/C24H31NO4S/c1-23-11-9-18(29-30(26,27)28)14-17(23)5-6-19-21-8-7-20(16-4-3-13-25-15-16)24(21,2)12-10-22(19)23/h3-5,7,13,15,18-19,21-22H,6,8-12,14H2,1-2H3,(H,26,27,28)/t18-,19-,21-,22-,23-,24+/m0/s1

HIDE SMILES / InChI

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
0.044 µM [IC50]
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
ZYTIGA

Approved Use

ZYTIGA is a CYP17 inhibitor indicated for use in combination with prednisone for the treatment of patients with metastatic castration-resistant prostate cancer who have received prior chemotherapy containing docetaxel.

Launch Date

2011
Name Type Language
ABIRATERONE SULFATE
Common Name English
ABIRATERONE METABOLITE M12
Common Name English
(3S,8R,9S,10R,13S,14S)-10,13-DIMETHYL-17-(PYRIDIN-3-YL)-2,3,4,7,8,9,10,11,12,13,14,15-DODECAHYDRO-1H-CYCLOPENTA(A)PHENANTHREN-3-YL HYDROGEN SULFATE
Systematic Name English
Code System Code Type Description
FDA UNII
WZ5U45K71V
Created by admin on Sat Dec 16 09:30:39 GMT 2023 , Edited by admin on Sat Dec 16 09:30:39 GMT 2023
PRIMARY
PUBCHEM
91827106
Created by admin on Sat Dec 16 09:30:39 GMT 2023 , Edited by admin on Sat Dec 16 09:30:39 GMT 2023
PRIMARY