Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H12O2 |
| Molecular Weight | 224.2546 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O=C1CC(OC2=CC=CC=C12)C3=CC=CC=C3
InChI
InChIKey=ZONYXWQDUYMKFB-UHFFFAOYSA-N
InChI=1S/C15H12O2/c16-13-10-15(11-6-2-1-3-7-11)17-14-9-5-4-8-12(13)14/h1-9,15H,10H2
Flavanone is the basic chemical skeleton for the class of compounds known as Flavanoids. Flavonoids are naturally occurring secondary plant metabolites. They are mainly found in cereals and herbs. In the western diet, the estimated daily intake of flavonoids is in the range of 20 -50 mg per day. Flavonoids as a class generally have effects on CYP (P450) activity, and therefore may affect drug metabolisms.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases. | 2001 |
|
| Localization of flavonoid enzymes in Arabidopsis roots. | 2001 Jul |
|
| 8-dimethylallylnaringenin 2'-hydroxylase, the crucial cytochrome P450 mono-oxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells. | 2001 Nov |
|
| Comparative genomics and regulatory evolution: conservation and function of the Chs and Apetala3 promoters. | 2001 Oct |
|
| Coumaronochromones and flavanones from Euchresta formosana roots. | 2002 Aug |
|
| Enantiomer separation of flavour and fragrance compounds by liquid chromatography using novel urea-covalent bonded methylated beta-cyclodextrins on silica. | 2002 Aug 30 |
|
| Plant defense genes associated with quantitative resistance to potato late blight in Solanum phureja x dihaploid S. tuberosum hybrids. | 2002 Jun |
|
| Antidiabetic principles of natural medicines. V. Aldose reductase inhibitors from Myrcia multiflora DC. (2): Structures of myrciacitrins III, IV, and V. | 2002 Mar |
|
| Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes. | 2002 Nov |
|
| Duplication and adaptive evolution of the chalcone synthase genes of Dendranthema (Asteraceae). | 2002 Oct |
|
| Arabidopsis UVR8 regulates ultraviolet-B signal transduction and tolerance and contains sequence similarity to human regulator of chromatin condensation 1. | 2002 Sep |
|
| Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables. | 2002 Sep |
|
| Inhibition of [3H]-LSD binding to 5-HT7 receptors by flavonoids from Scutellaria lateriflora. | 2003 Apr |
|
| Cholinesterase inhibitory constituents from Onosma hispida. | 2003 Apr |
|
| Enzymatic formation of unnatural novel polyketides from alternate starter and nonphysiological extension substrate by chalcone synthase. | 2003 Apr 17 |
|
| Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins. | 2003 Feb |
|
| Arabidopsis ICX1 is a negative regulator of several pathways regulating flavonoid biosynthesis genes. | 2003 Feb |
|
| Recent advances in the biosynthesis and accumulation of anthocyanins. | 2003 Jun |
|
| Benzophenone synthase and chalcone synthase from Hypericum androsaemum cell cultures: cDNA cloning, functional expression, and site-directed mutagenesis of two polyketide synthases. | 2003 Jun |
|
| Activity-guided isolation of the chemical constituents of Muntingia calabura using a quinone reductase induction assay. | 2003 Jun |
|
| Gradual shifts in sites of free-auxin production during leaf-primordium development and their role in vascular differentiation and leaf morphogenesis in Arabidopsis. | 2003 Mar |
|
| Tracing floral adaptations from ecology to molecules. | 2003 Mar |
|
| Influence of industrial processing on orange juice flavanone solubility and transformation to chalcones under gastrointestinal conditions. | 2003 May 7 |
Sample Use Guides
High-flavanone (305 mg) 100% orange juice and an equicaloric low-flavanone (37 mg) orange-flavored cordial (500 mL) were consumed daily for 8 weeks by 37 healthy older adults. The global cognitive function was significantly better after 8 weeks of consumption relative to controls.
Route of Administration:
Oral
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
487-26-3
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
50393
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
207-654-8
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
5070
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
WX22P730FB
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
10251
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY | |||
|
DTXSID9022318
Created by
admin on Sat Dec 16 09:05:29 GMT 2023 , Edited by admin on Sat Dec 16 09:05:29 GMT 2023
|
PRIMARY |
SUBSTANCE RECORD
