Alfurolol is a beta-adrenergic blocker. It is non-selective blocking drug with both intrinsic sympathomimetic activity and weak membrane stabilizing activity. There is also evidence that, unlike other beta-blocking drugs, only extremely small amounts of alfurolol cross the blood-brain barrier: because of this property, it has very little effect on the CNS. Alfurolol consistently produced a reduction in exercise heart rate at all times during the seven-hour period of observation, and the reductions were significantly different from the corresponding values after placebo treatment. Alfurolol is active both on heart rate and systolic pressure.