PROSTAGLANDIN F1

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H36O5
Molecular Weight	356.4968
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O

InChI

InChIKey=DZUXGQBLFALXCR-CDIPTNKSSA-N

InChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/1986158

Prostaglandin F1 alpha is a stable metabolite of prostacyclin, a powerful inhibitor of platelet aggregation as well as a potent vasodilator. Prostaglandin F1a is derived mainly from prostaglandin E1 and is metabolized to 6-keto prostaglandin F1a. It was shown, that the fluctuating prostaglandin F1 alpha levels were of clinical significance in the management of vasomotor tone and platelet function, common problems in the care and the prevention of hemorrhage in critically ill infants.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Role of prostaglandins in delayed cerebral ischemia after subarachnoid hemorrhage.	1992 Jan	1738450

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Name

Type

Language

PROSTAGLANDIN F1

Common Name

English

PROSTAGLANDIN F1ALPHA

Common Name

English

CYCLOPENTANEHEPTANOIC ACID, 3,5-DIHYDROXY-2-(3-HYDROXY-1-OCTENYL)-

Common Name

English

PROSTAGLANDIN F1.ALPHA.

Common Name

English

PROST-13-EN-1-OIC ACID, 9,11,15-TRIHYDROXY-, (9-.ALPHA.,11-.ALPHA.,13E,15S)

Common Name

English

Classification Tree Code System Code

LOINC

10583-3