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Details

Stereochemistry ABSOLUTE
Molecular Formula C20H36O5
Molecular Weight 356.4968
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of PROSTAGLANDIN F1

SMILES

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1CCCCCCC(O)=O

InChI

InChIKey=DZUXGQBLFALXCR-CDIPTNKSSA-N
InChI=1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-19,21-23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,18-,19+/m0/s1

HIDE SMILES / InChI

Description

Prostaglandin F1 alpha is a stable metabolite of prostacyclin, a powerful inhibitor of platelet aggregation as well as a potent vasodilator. Prostaglandin F1a is derived mainly from prostaglandin E1 and is metabolized to 6-keto prostaglandin F1a. It was shown, that the fluctuating prostaglandin F1 alpha levels were of clinical significance in the management of vasomotor tone and platelet function, common problems in the care and the prevention of hemorrhage in critically ill infants.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

PubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown