IMICLOPAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H32ClN5OS
Molecular Weight	486.072
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IMICLOPAZINE

Structure Search

SMILES

CN1CCN(CCN2CCN(CCCN3C4=CC=CC=C4SC5=C3C=C(Cl)C=C5)CC2)C1=O

InChI

InChIKey=OCDYNPAUUKDNOR-UHFFFAOYSA-N

InChI=1S/C25H32ClN5OS/c1-27-11-17-30(25(27)32)18-16-29-14-12-28(13-15-29)9-4-10-31-21-5-2-3-6-23(21)33-24-8-7-20(26)19-22(24)31/h2-3,5-8,19H,4,9-18H2,1H3

HIDE SMILES / InChI

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/4146043 | https://www.ncbi.nlm.nih.gov/pubmed/5810234 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19651216&CC=BE&NR=668972A&KC=A

Imiclopazine is a phenothiazines derivative patented by Asta-Werke A.-G. as strong sedative and antiemetic agent. Imiclopazine was studied for treatment of schizophrenia but was never marketed.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Treatment of schizophrenia with imiclopazine, pimozide, imagotan and trifluorperidol. Comparative study].	1973 Jan-Feb	4146043

Patents

Patents

Name

Type

Language

IMICLOPAZINE

Official Name

English

1-(2-(4-(3-(2-CHLOROPHENOTHIAZIN-10-YL)PROPYL)-1-PIPERAZINYL)ETHYL)-3-METHYL-2-IMIDAZOLIDINONE

Systematic Name

English

imiclopazine [INN]

Common Name

English

IMICLOPAZINE [MI]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C740

Created by admin on Sat Dec 16 17:56:15 GMT 2023 , Edited by admin on Sat Dec 16 17:56:15 GMT 2023

NCI_THESAURUS

C29710

Created by admin on Sat Dec 16 17:56:15 GMT 2023 , Edited by admin on Sat Dec 16 17:56:15 GMT 2023

Code System Code Type Description

ChEMBL

CHEMBL2105043

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MESH

C002916

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DRUG CENTRAL

3758

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MERCK INDEX

m245

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Merck Index

EPA CompTox

DTXSID60864024

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SMS_ID

100000083916

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NCI_THESAURUS

C65892

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EVMPD

SUB08142MIG

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PUBCHEM

23896

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CAS

7224-08-0

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INN

2369

Created by admin on Sat Dec 16 17:56:15 GMT 2023 , Edited by admin on Sat Dec 16 17:56:15 GMT 2023

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FDA UNII

WGL8B3MDAS

Created by admin on Sat Dec 16 17:56:15 GMT 2023 , Edited by admin on Sat Dec 16 17:56:15 GMT 2023

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ACTIVE MOIETY


					WGL8B3MDAS