Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H18FN3.2ClH |
| Molecular Weight | 368.276 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.FC1=CC2=C(NC3=C2CN(CCC4=CC=NC=C4)CC3)C=C1
InChI
InChIKey=JZKBIAMJBKEKGP-UHFFFAOYSA-N
InChI=1S/C18H18FN3.2ClH/c19-14-1-2-17-15(11-14)16-12-22(10-6-18(16)21-17)9-5-13-3-7-20-8-4-13;;/h1-4,7-8,11,21H,5-6,9-10,12H2;2*1H
Carvotroline [WY 47791] is a novel γ-carboline derivative with a preclinical profile suggestive of antipsychotic activity. Carvotroline has an affinity for the dopamine D2 receptor and cortical 5-HT2 receptor that is ten times greater than serotonin. Carvotroline administration to rats leads to a decrease of plasma corticosterone levels and demonstrated a moderating effect on the rotational-stress induced rise in plasma corticosterone levels.
Approval Year
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13772459
Created by
admin on Fri Dec 15 15:58:02 GMT 2023 , Edited by admin on Fri Dec 15 15:58:02 GMT 2023
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WGF75067BR
Created by
admin on Fri Dec 15 15:58:02 GMT 2023 , Edited by admin on Fri Dec 15 15:58:02 GMT 2023
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DTXSID70147991
Created by
admin on Fri Dec 15 15:58:02 GMT 2023 , Edited by admin on Fri Dec 15 15:58:02 GMT 2023
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107266-20-6
Created by
admin on Fri Dec 15 15:58:02 GMT 2023 , Edited by admin on Fri Dec 15 15:58:02 GMT 2023
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PRIMARY |
ACTIVE MOIETY
SUBSTANCE RECORD
