Resigratinib

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H27F2N7O3
Molecular Weight	523.5345
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC1=C(C(N)=O)C(=NN1[C@H]2C[C@H](COC)N(C2)C(=O)C=C)C#CC3=C(F)C=C4N(C=NC4=C3F)C5CC5

InChI

InChIKey=YXVDEILMUVTDMK-JKSUJKDBSA-N

InChI=1S/C26H27F2N7O3/c1-4-21(36)33-11-15(9-16(33)12-38-3)35-26(30-2)22(25(29)37)19(32-35)8-7-17-18(27)10-20-24(23(17)28)31-13-34(20)14-5-6-14/h4,10,13-16,30H,1,5-6,9,11-12H2,2-3H3,(H2,29,37)/t15-,16+/m0/s1

HIDE SMILES / InChI

Approval Year

Name

Type

Language

resigratinib [INN]

Preferred Name

English

Resigratinib

Official Name

English

3-[2-(1-Cyclopropyl-4,6-difluoro-1H-benzimidazol-5-yl)ethynyl]-1-[(3S,5R)-5-(methoxymethyl)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-5-(methylamino)-1H-pyrazole-4-carboxamide

Systematic Name

English

1H-Pyrazole-4-carboxamide, 3-[2-(1-cyclopropyl-4,6-difluoro-1H-benzimidazol-5-yl)ethynyl]-1-[(3S,5R)-5-(methoxymethyl)-1-(1-oxo-2-propen-1-yl)-3-pyrrolidinyl]-5-(methylamino)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

162381323