| Stereochemistry | RACEMIC |
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | 294.3462 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(=CC(OC)=C1OC)C(=O)NC2CCCNC2
InChI
InChIKey=YSIITVVESCNIPR-UHFFFAOYSA-N
InChI=1S/C15H22N2O4/c1-19-12-7-10(8-13(20-2)14(12)21-3)15(18)17-11-5-4-6-16-9-11/h7-8,11,16H,4-6,9H2,1-3H3,(H,17,18)
Troxipide is a gastric cytoprotective agent used for the treatment of gastritis and gastric uclers in Japan, India, China and South Korea. Troxipide has a mode of action different from that for other anti-gastric agents: it does not inhibit acid secretion and does not have acid neutralizing activity. It exerts its activity by increasing mucus production, cytoprotective prostaglandin secretion, regeneration of collagen fibers, reducing inflammatory mediator induced neutrophil migration and reactive oxygen species generation in gastric mucosa, enhancing gastric mucosal metabolism and microcirculation.
Originator
Approval Year
Doses
AEs
PubMed
Patents
Sample Use Guides
The usual adult dosage for oral use is 100 mg of troxipide (one tablet or 0.5 g of fine granules) three times daily after meals.
Route of Administration:
Oral
ACTIVE MOIETY
