Details
Stereochemistry | ACHIRAL |
Molecular Formula | C7H9N3O3S |
Molecular Weight | 215.23 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)NS(=O)(=O)C1=CC=C(N)C=C1
InChI
InChIKey=WVAKABMNNSMCDK-UHFFFAOYSA-N
InChI=1S/C7H9N3O3S/c8-5-1-3-6(4-2-5)14(12,13)10-7(9)11/h1-4H,8H2,(H3,9,10,11)
DescriptionSources: https://www.rlsnet.ru/mnn_index_id_677.htmCurator's Comment: The description was created based on several sources, including
https://www.drugs.com/international/sulfacarbamide.html | https://www.ncbi.nlm.nih.gov/pubmed/13154430 | http://farmaspravka.com/sulfakarbamid-sulfacarbamide | https://www.ncbi.nlm.nih.gov/pubmed/14817507
Sources: https://www.rlsnet.ru/mnn_index_id_677.htm
Curator's Comment: The description was created based on several sources, including
https://www.drugs.com/international/sulfacarbamide.html | https://www.ncbi.nlm.nih.gov/pubmed/13154430 | http://farmaspravka.com/sulfakarbamid-sulfacarbamide | https://www.ncbi.nlm.nih.gov/pubmed/14817507
Sulfacarbamide is an antimicrobial agent that has been investigated as a therapeutic biochemical for diabetes treatment. Sulfacaramide - has a bacteriostatic effect due to competitive antagonism with PABA, preventing its inclusion in Dihydrofolic acid, which leads to a violation of the synthesis of tetrahydrofolic acid. Thus, the synthesis of nucleic acids is broken, as a result of which the growth and multiplication of microorganisms are suppressed.
Originator
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
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Target ID: GO:0046656 Sources: https://www.rlsnet.ru/mnn_index_id_677.htm |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Primary | Sulfasalazine-EH Approved UseUnknown |
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Sources: https://www.rlsnet.ru/mnn_index_id_677.htm |
Curative | Sulfasalazine-EH Approved UseUnknown |
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Sources: https://www.rlsnet.ru/mnn_index_id_677.htm |
Curative | Sulfasalazine-EH Approved UseUnknown |
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Curative | Sulfasalazine-EH Approved UseUnknown |
Sample Use Guides
In Vivo Use Guide
Sources: http://farmaspravka.com/sulfakarbamid-sulfacarbamide
For adults, a single dose is 0.5-1 g 3-5 r / day. The maximum single dose is 2 g, the maximum daily intake is 7 g. The course of treatment is 6-14 days. For children, the daily dose is 1-2.5 g (in 4-5 receptions).
Route of Administration:
Oral
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Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C97936
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m10332
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SUB10685MIG
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78438
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11033
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C152453
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37333
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208-922-7
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DTXSID1046425
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CHEMBL139877
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W6CD25Z4QR
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ACTIVE MOIETY