Details
Stereochemistry | ACHIRAL |
Molecular Formula | C13H12N2O2.ClH |
Molecular Weight | 264.708 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 1 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.OC(=O)\C=C\C1=CC=C(CN2C=CN=C2)C=C1
InChI
InChIKey=CWKFWBJJNNPGAM-IPZCTEOASA-N
InChI=1S/C13H12N2O2.ClH/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15;/h1-8,10H,9H2,(H,16,17);1H/b6-5+;
Approval Year
Targets
Primary Target | Pharmacology | Condition | Potency |
---|---|---|---|
Target ID: P24557|||Q8IUN1|||Q9HD82 Gene ID: 6916.0 Gene Symbol: TBXAS1 Target Organism: Homo sapiens (Human) Sources: http://www.ncbi.nlm.nih.gov/pubmed/14720071 |
11.0 nM [IC50] |
Conditions
Condition | Modality | Targets | Highest Phase | Product |
---|---|---|---|---|
Palliative | DOMENAN Approved UseUnknown |
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Primary | XANBON Approved UseCerebral vasospasm and ischaemia following surgical management of subarachnoid haemorrhage. |
Sample Use Guides
1 tablet (200 mg of the active ingredient) at a time, twice a day after breakfast and before bedtime (for asthma). Intravenous infusion of 80mg, twice a day, solute in 500ml normal saline or 5% glucose solution (cerebral vasospasm).
Route of Administration:
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78712-43-3
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100000085534
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SUB03603MIG
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W222U960HS
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m8349
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DTXSID9045506
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DBSALT002122
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6438130
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PARENT (SALT/SOLVATE)
SUBSTANCE RECORD