| Stereochemistry | RACEMIC |
| Molecular Formula | C11H16ClN3O4S2 |
| Molecular Weight | 353.845 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)CC1NC2=CC(Cl)=C(C=C2S(=O)(=O)N1)S(N)(=O)=O
InChI
InChIKey=HGBFRHCDYZJRAO-UHFFFAOYSA-N
InChI=1S/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17)
Buthiazide (or Butizide) is a diuretic of the thiazide class. It was used for the treatment of mild to moderate essential hypertension. Buthiazide reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism.
Originator
Approval Year
Targets
| Primary Target | Pharmacology | Condition | Potency |
|---|---|---|---|
PubMed
ACTIVE MOIETY
