ENFLICOXIB

NS(=O)(=O)C1=CC=C(C=C1)N2N=C(CC2C3=CC=C(F)C=C3F)C(F)(F)F

InChIKey=ZZMJXWXXMAAPLI-UHFFFAOYSA-N

InChI=1S/C16H12F5N3O2S/c17-9-1-6-12(13(18)7-9)14-8-15(16(19,20)21)23-24(14)10-2-4-11(5-3-10)27(22,25)26/h1-7,14H,8H2,(H2,22,25,26)

PubMed

Title	Date	PubMed
Development and validation of two chromatographic methods for the quantification of E-6087 and one of its metabolites, E-6132, in rat plasma.	2001 Mar	11248483
Pharmacokinetics of E-6087, a new anti-inflammatory agent, in rats and dogs.	2001 Sep	11754039
Enantioseparation of novel COX-2 anti-inflammatory drugs by capillary electrophoresis using single and dual cyclodextrin systems.	2002 Jun	12179991
Determination of enantiomeric purity of a novel COX-2 anti-inflammatory drug by capillary electrophoresis using single and dual cyclodextrin systems.	2003 May	12731028

Patents

Name

Type

Language

ENFLICOXIB

Official Name

English

1-(4-AMINOSULFONYLPHENYL)-5-(2,4-DIFLUOROPHENYL)-4,5-DIHYDRO-3-TRIFLUOROMETHYL-1H-PYRAZOLE

Systematic Name

English

BENZENESULFONAMIDE, 4-(5-(2,4-DIFLUOROPHENYL)-4,5-DIHYDRO-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL)-

Systematic Name

English

enflicoxib [INN]

Common Name

English

E-6087

Code

English

4-(3-(2,4-DIFLUOROPHENYL)-5-(TRIFLUOROMETHYL)-3,4-DIHYDROPYRAZOL-2-YL)BENZENESULFONAMIDE

Systematic Name

English

E-6087, (±)-

Code

English

Code System Code Type Description

PUBCHEM

9953093