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Details

Stereochemistry ACHIRAL
Molecular Formula ClO4
Molecular Weight 99.451
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge -1

SHOW SMILES / InChI
Structure of PERCHLORATE ION

SMILES

[O-]Cl(=O)(=O)=O

InChI

InChIKey=VLTRZXGMWDSKGL-UHFFFAOYSA-M
InChI=1S/ClHO4/c2-1(3,4)5/h(H,2,3,4,5)/p-1

HIDE SMILES / InChI

Description

Perchloric acid is a strong acid used for complete digestions of organic material. To prevent injury, goggles or face shield, gloves, and apron must be worn. Perchloric acid must not be mixed with any other waste and should be stored separately from the other chemicals.

Approval Year

1974
168
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
PERCHLORACAP

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Application of perchloric acid technique to protozoa.
1949 Dec 16
Perchloric acid in the cytochemistry of pentose nucleic acid.
1949 Nov 4
Cell necrosis and apoptosis are differentially regulated during goitre development and iodine-induced involution.
2002 Feb
Functional activity of human sodium/iodide symporter in tumor cell lines.
2003 Feb
Probasin promoter (ARR(2)PB)-driven, prostate-specific expression of the human sodium iodide symporter (h-NIS) for targeted radioiodine therapy of prostate cancer.
2003 Nov 15
Human 3'-phosphoadenosine 5'-phosphosulfate synthetase (isoform 1, brain): kinetic properties of the adenosine triphosphate sulfurylase and adenosine 5'-phosphosulfate kinase domains.
2004 Apr 13
Establishment of a human hepatocellular carcinoma cell line highly expressing sodium iodide symporter for radionuclide gene therapy.
2004 Sep
The BeWo choriocarcinoma cell line as a model of iodide transport by placenta.
2005 May
Development of a rat dosimetry model for bromate.
2006 Apr 17
Effects of prolonged exposure to perchlorate on thyroid and reproductive function in zebrafish.
2007 Apr
Low-dose effects of ammonium perchlorate on the hypothalamic-pituitary-thyroid axis of adult male rats pretreated with PCB126.
2007 Jun
Duox expression and related H2O2 measurement in mouse thyroid: onset in embryonic development and regulation by TSH in adult.
2007 Mar
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 1. Effects on the brain.
2007 May 31
Identification of gene expression indicators for thyroid axis disruption in a Xenopus laevis metamorphosis screening assay. Part 2. Effects on the tail and hindlimb.
2007 May 31
Perchlorate and ethylenethiourea induce different histological and molecular alterations in a non-mammalian vertebrate model of thyroid goitrogenesis.
2009 Jan 27
Thyroid hormone may regulate mRNA abundance in liver by acting on microRNAs.
2010 Aug 13
Perchlorate transport and inhibition of the sodium iodide symporter measured with the yellow fluorescent protein variant YFP-H148Q/I152L.
2010 Mar 15
Inhibition of thyroid hormone release from cultured amphibian thyroid glands by methimazole, 6-propylthiouracil, and perchlorate.
2010 Nov
Goitrogenic anions, thyroid-stimulating hormone, and thyroid hormone in infants.
2010 Sep
The effects of perchlorate on thyroidal gene expression are different from the effects of iodide deficiency.
2011
Biomarker expression in lung of rabbit with pulmonary fibrosis induced by ammonium perchlorate.
2011 Apr
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.
2012 Aug
Patents

Patents

03950331
20
03975412
6
03977981
6
04031088
19
04051260
13
04162913
15
04201879
6
04475992
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04495357
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04518774
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04519938
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04532355
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04596809
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04656310
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04663260
6
04833209
6
04954518
13
04990517
10
05110945
10
05145893
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05191108
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05200518
8
05220042
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05663364
6
05670650
6
05770605
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05981580
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05998463
8
07022716
9
07132416
6
07153873
7
07163951
8
07169407
10
07273857
11
07300928
11
07429660
7
07626021
10
07662861
6
07829558
6
08030501
6
08124783
8
08304544
8
08785638
6
08791108
6
08835632
6
Name Type Language
PERCHLORATE ION
Common Name English
PERCHLORATE ION(1-)
Common Name English
PERCHLORIC ACID, ION(1-)
Common Name English
PERCHLORATE
Systematic Name English
Code System Code Type Description
MESH
C494474
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
FDA UNII
VLA4NZX2P4
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
PUBCHEM
123351
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
EPA CompTox
DTXSID6024252
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
CHEBI
49706
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
CAS
14797-73-0
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
DRUG BANK
DB03138
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
WIKIPEDIA
PERCHLORATE
Created by admin on Sat Dec 16 01:42:55 GMT 2023 , Edited by admin on Sat Dec 16 01:42:55 GMT 2023
PRIMARY
ACTIVE MOIETY
Structure of PERCHLORATE ION
NIH
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