LOFENDAZAM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C15H13ClN2O
Molecular Weight	272.73
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of LOFENDAZAM

Structure Search

SMILES

ClC1=CC=C2NCCC(=O)N(C3=CC=CC=C3)C2=C1

InChI

InChIKey=IUJQOUHDFKALCY-UHFFFAOYSA-N

InChI=1S/C15H13ClN2O/c16-11-6-7-13-14(10-11)18(15(19)8-9-17-13)12-4-2-1-3-5-12/h1-7,10,17H,8-9H2

HIDE SMILES / InChI

Description
Sources: DOI: 10.1002/mrc.1270150414 | https://www.ncbi.nlm.nih.gov/pubmed/1043 | Müller, W.E., Müller, W.E. (1987) The Benzodiazepine Receptor, page 47, retrieved from: https://books.google.ru/books?id=bOo8AAAAIAAJ

Lofendazam is partial benzodiazepine agonist. It has been widely tested as a psychotherapeutic drug. In particular, as an anxiety treatment agent.

Approval Year

PubMed

PubMed

Title	Date	PubMed
[Clinical trial of a novel benzodiazepine derivative in a double-blind study using the Wittenborn psychiatric rating scale (author's transl)].	1975 Oct	1043

Patents

Patents

Name

Type

Language

LOFENDAZAM

Official Name

English

8-CHLORO-1,3,4,5-TETRAHYDRO-1-PHENYL-2H-1,5-BENZODIAZEPIN-2-ONE

Systematic Name

English

lofendazam [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29710

Created by admin on Sat Dec 16 18:03:08 GMT 2023 , Edited by admin on Sat Dec 16 18:03:08 GMT 2023

Code System Code Type Description

PUBCHEM

71709

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NCI_THESAURUS

C66026

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EVMPD

SUB08555MIG

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WIKIPEDIA

LOFENDAZAM

Created by admin on Sat Dec 16 18:03:08 GMT 2023 , Edited by admin on Sat Dec 16 18:03:08 GMT 2023

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ChEMBL

CHEMBL2107159

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FDA UNII

V7O53S50SN

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INN

4014

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ECHA (EC/EINECS)

249-488-9

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CAS

29176-29-2

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EPA CompTox

DTXSID30183436

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SMS_ID

100000081999

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ACTIVE MOIETY


					V7O53S50SN