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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H16N4O6
Molecular Weight 324.2893
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of LEVOFURALTADONE

SMILES

[O-][N+](=O)C1=CC=C(O1)\C=N\N2C[C@H](CN3CCOCC3)OC2=O

InChI

InChIKey=YVQVOQKFMFRVGR-NGPAHMQLSA-N
InChI=1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+/t11-/m0/s1

HIDE SMILES / InChI

Description

Levofuraltadone is the nitrofurane used for the treatment of trypanosomiasis. It has been shown to be effective in mice and polyneuritis, a serious side effect of nitrofurazone therapy, is less frequent with levofuraltadone. Nevertheless, levofuraltadone is a very toxic agent and it has never been commercially produced.

Approval Year

PubMed

Sample Use Guides

In Vivo Use Guide
30 mg/kg each day for 15 days followed by 10 mg/kg/day for 3 months
Route of Administration: Unknown